Electrophysiological Evaluation of Visual Hallucination in Parkinson’s Disease Psychosis
Objective: Our understanding of the psychosis in Parkinson’s disease (PDPsy) is incomplete, and standard of care treatment with antipsychotics has its limitations. Neuroimaging and histopathology in PDPsy reveal that visual hallucinations (VHs), the hallmark of psychosis in PDPsy, arise…Genotype Matters: Vagus Nerve Atrophy in GBA-Associated Parkinson’s Disease
Objective: The aim of this study is to compare the right and left vagus nerve (VN) cross-sectional area (CSA) and autonomic symptoms in patients with…A Case Report: Optimising Motor and Non-Motor Control in Advanced Parkinson’s Disease: The Role of Foslevodopa/Foscarbidopa After Deep Brain Stimulation
Objective: To investigate the combined use of continuous subcutaneous foslevodopa/foscarbidopa and deep-brain stimulation in managing advanced Parkinsons Disease. Background: Continuous foslevodopa/foscarbidopa subcutaneous (SC) infusion has been shown…Wearable-Derived Gait Biomarkers Predict Disease Severity and Quality of Life in Parkinson’s Disease: A Machine Learning and Mediation Analysis
Objective: To investigate whether wearable-derived gait biomarkers predict disease severity and health-related quality of life in Parkinson’s disease (PD) and to examine the mediating role…Item – Level Drivers of Certification Failure in the MDS-UPDRS Motor Examination: A Five-Year Global Analysis
Objective: To identify individual Part III items that disproportionately contribute to first-attempt certification failure and to evaluate the stability of these patterns over five years.…Effect of subthalamic nucleus deep brain stimulation on heart rate variability in Parkinson’s disease
Objective: To characterize the effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on cardiac autonomic regulation at rest and during paced deep breathing in advanced…Digital Facial Movement Analysis in Hemifacial Spasm: Potential and Limitations as a Clinical Biomarker
Objective: To evaluate the potential use of digital biomarkers in the treatment assessment of hemifacial spasm (HFS) using botulinum toxin, also assessed with conventional methods…The enteric footprint of de novo parkinson’s disease cohort: constipation, inflammation, and nulisa biomarker profiling.
Objective: This study aimed to analyze constipation symptoms and blood, CSF and fecal biomarkers, including a High-plex Profiling of Inflammatory Proteins (NULISA) in a de novo PD cohort. Background: Parkinson’s disease…Central Nervous System Lesioning Procedures For Dystonia In The Deep Brain Stimulation Era: A Systematic Review
Objective: To evaluate the contemporary clinical role of central nervous system (CNS) lesioning procedures for dystonia in the deep brain stimulation (DBS) era, when DBS…Systemic antioxidant response to bilateral anodal transcranial direct current stimulation in Parkinson’s disease: findings from a pilot randomized controlled study
Objective: To investigate whether repeated sessions of bilateral anodal tDCS can influence circulating antioxidant enzyme levels and fatigue severity in individuals with Parkinson’s disease. Background:…
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