Knee Extensor Strength Is Associated with Torque Generation and Mobility in Parkinsonian Disorders
Objective: To examine associations among knee extensor strength (KES), torque generation during knee extension quantified by the area under the torque–time curve (AUC), and functional…Psychometric Assessment of a Modified Version of the Unified Multiple System Atrophy Rating Scale Part I
Objective: To evaluate the psychometric properties, reliability, and validity of a modified version of UMSARS Part I (mUMSARS), collapsing response categories 0 and 1 and…Expanding Parkinson’s Disease Genomics in East Africa
Objective: To establish a deeply phenotyped Parkinson’s disease (PD) cohort in East Africa and generate genomic and biosample resources for discovery and replication of ancestry-specific…Analyzing the classification of 767 GBA1 variants to guide GBA1 PD risk prediction
Objective: To assess the consistency of GBA1 variant classification across large Parkinson’s disease (PD) and Gaucher disease (GD) cohorts and determine how variant-specific biochemical data…A Comprehensive Analysis of Advanced Deep Brain Stimulation Programming Strategies
Objective: To evaluate clinical rationale and outcomes of advanced deep brain stimulation (DBS) programming for movement disorders. Background: DBS is an effective treatment for medication…Effectiveness aNd use of fosleVOdopa-foscarbidopa in advanced Parkinson disease in real Life setting in France (ENVOL study): interim analysis
Objective: To assess the real-world (RW) effectiveness of continuous subcutaneous infusion of foslevodopa/foscarbidopa (LDp/CDp) over a 12-month follow-up. Background: LDp/CDp is a continuous 24-hour subcutaneous…Diffusion MRI Markers of Neural Reserve: Interaction Between Callosal Integrity and Clinical Vulnerability After Functional Neurosurgery in Parkinson’s Disease
Objective: To evaluate whether diffusion MRI markers of callosal integrity, together with baseline clinical vulnerability, are associated with cognitive trajectory after functional neurosurgical treatment in…The Clinical and Neuropathological Factors Associated with Brain Atrophy in CSF1R-RD.
Objective: To characterize the clinical and neuropathological factors associated with brain atrophy in CSF1R-related disorder (CSF1R-RD). Background: CSF1R-RD is a rare, fatal autosomal dominant leukoencephalopathy…Multilevel Structure-Function Coupling Reveals Network Signatures of Remission in Paroxysmal Kinesigenic Dyskinesia
Objective: To provide a novel neurobiological framework for understanding and predicting clinical trajectories in PKD. Background: Paroxysmal kinesigenic dyskinesia (PKD) causes brief, movement-triggered dystonic or…Utility of the Short Cognitive and Neuropsychiatric Assessment Scale (ShoCo) in a Multiethnic Asian Cohort of Patients with Progressive Supranuclear Palsy
Objective: To assess the clinical utility of the Short Cognitive and Neuropsychiatric Assessment (ShoCo) scale in a multi-ethnic Malaysian cohort of patients with progressive supranuclear…
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