Multivariate Cognitive Markers of Dementia Progression in Parkinson’s Disease
Objective: To identify neuropsychological markers at the PD-MCI stage associated with the progression severity to PDD using a multivariate, data-driven approach with longitudinal validation. Background:…Motor Trajectory in Parkinson’s Disease With Excessive Daytime Sleepiness: A Longitudinal Cohort Study
Objective: To investigate the longitudinal association between excessive daytime sleepiness (EDS) and motor progression in Parkinson’s disease (PD). Background: EDS is a common non-motor symptom…Demographic And Clinical Characteristics Of Advanced Parkinson’s Disease Patients Receiving Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) In The ELEGANCE Study: An Updated Interim Analysis
Objective: To describe the latest demographic and clinical profiles of patients with advanced Parkinson’s disease (aPD) enrolled in the ELEGANCE study who have received treatment…Toward a Standardized Measure of Parkinson’s Disease Psychosis: Preliminary Inter-Rater Reliability of the MDS Parkinson’s Disease Psychosis Rating Scale (MDS-PDPRS)
Objective: To evaluate the inter-rater reliability (IRR) of the MDS-PDPRS in a pilot clinimetric cohort. Background: No validated outcome assessment exists to measure the functional…An Elevation in the Serum Biomarker pTau-181 May Identify Progressive Supranuclear Palsy Pathology
Objective: To report three cases of progressive supranuclear palsy (PSP) with significantly elevated pTau-181 levels on serum testing. Background: According to the MDS-endorsed PSP Study…Unilateral Deep Brain Stimulation For Essential Tremor: Compromise or Long-term Effective Treatment?
Objective: To explore the differences in short-term (1-year), mid-term (2–5 years), and long-term (≥6 years) HRQoL and tremor outcomes in ET patients treated with unilateral…Brain-First and Body-First Model Translated to Individual-Level Characterization in Parkinson’s Disease: Multimodal Imaging and Clinical Approach
Objective: To determine whether the body-first versus brain-first hypothesis of Parkinson’s disease (PD) can be reliably applied at the individual patient level using multimodal clinical…Augmenting PD GENEration Genotyping with Continuous Digital Monitoring for Parkinson’s Disease
Objective: To link PD GENEration genetic testing and counseling with continuous digital phenotyping to characterize genotype-associated mobility change, reduce access barriers, and support recruitment for…Objective detection of morning bradykinesia in Parkinson’s Disease using a wearable inertial sensor
Objective: To evaluate whether a wearable inertial sensor (WIS) can detect and characterize morning bradykinesia (MB) in patients with Parkinson’s disease (PD). Background: Morning bradykinesia…Prevalence of sarcopenic obesity and its association with non-motor symptoms in early Parkinson’s disease
Objective: To investigate the prevalence of sarcopenia, obesity, and sarcopenic obesity (SO) and their associations with non-motor symptoms in patients with early Parkinson’s disease (PD).…
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