2026 International Congress » Parkinson's Disease: Disease mechanisms

Boosting cerebellum/M1 and PPC/M1 communication via tACS to improve cued gait in Parkinson’s disease patients unresponsive to auditory cueing strategies.

E. Pelosin, A. Botta, V. Romano, J. Nonnekes, M. Gilat, I. Maidan, A. Mirelman, L. Avanzino (Genova, Italy)

Circadian Regulator REV-ERBα Drives Microglial Lipid Metabolic Reprogramming and Cognitive Impairment in Parkinson‘s Disease

T. Deng (Guang Zhou, China)

Cortical Dynamics Underlying the Heterogeneous Dopamine Responsiveness of Rest Tremor in Parkinson’s Disease

X. Xu, Y. Zang, P. Chan (Beijing, China)

DCN-PPN Pathway Activation Improves Motor Dysfunction via Synaptic Plasticity in Parkinson’s Disease

L. Liao, Z. Zhang (Guangzhou, Guangdong Province, China)

Dysregulation of lysosomal lipid microdomains impairs autophagic flux in GBA-associated Parkinson’s disease

M. Chen, F. Liu, Y. Sun, Y. Yang, J. Wang (Shanghai, China)

Electroacupuncture Restores Cortico-striatal Synaptic Plasticity by Promoting STEP61 against 6-OHDA Induced Extrasynaptic NMDAR/TRPM4 Complex

Y. Zhang, L. Nie, J. Fan, L. Zhuang (Guangzhou, China)

Extracellular Neuromelanin Promotes Microglial Reactivity in Parkinson’s Disease

S. Smajic, V. Florentin, J. Ghelfi, K. Badanjak, S. Delcambre, C. Morris, J. Schwamborn, M. Spielmann, P. Antony, I. Goglia, A. Grünewald (Belval Esch-sur-Alzette, Luxembourg)

Frontal Cortical Reactivity Underlying Cue Responsiveness in Parkinson’s Disease: a TMS-EEG Study

I. Maidan, Z. Katzir, M. Bouter, M. Gilat, J. Nonnekes, L. Avanzino, E. Pelosin, A. Mirelman (Tel Aviv, Israel)

Latent Clinical States and Longitudinal Transitions in Prodromal Lewy Body Disease: A Data-Driven Analysis from the NaT-PROBE Study

K. Fuse, K. Hiraga, Y. Yada, K. Nakao, Y. Saito, T. Fukushima, D. Tamakoshi, T. Uematsu, T. Tsuboi, M. Suzuki, M. Sato, M. Yamamoto, H. Shimizu, M. Wakai, N. Honda, M. Katsuno (Nagoya, Japan)

LRRK2 G2019S Drives Lysosomal Lipid Remodeling and Inflammation in Human iPSC-Derived Microglia

M. Tziortziou, M. Jakubec, I. Goglia, K. Badanjak, P. Seibler, J. Penny, G. Dittmar, S. Pereira, P. Antony, E. Glaab, A. Grünewald (Esch-sur Alzette, Luxembourg)

Microglial Inflammatory Signaling Mediates Neuroimmune Dysregulation And Behavioral Dysfunction in A Parkinson’s Disease Model

M. M. Anwar, I. Ibrahim Laila (Cairo, Egypt)

Microstructural and functional abnormalities of Amygdala subregions in Parkinson’s Disease with impulse control disorder

C. Gan, Y. Yuan (Nanjing, China)

Modulated functional connectivity in patients with Parkinson’s disease by transcutaneous auricular acupoint Vagus Nerve Stimulation (taVNS)

XJ. Dan, SS. Gao, JL. Fang, P. Chan (45#Changchun Street, Xicheng District, Beijing, China)

Modulatory effects of bacterial-derived serine protease on pathological α-synuclein fibrillation in vitro

HJ. Yang, JI. Choi (Incheon, Republic of Korea)

Multi-Target Neurobiological Mechanisms of Acupuncture in Levodopa-Induced Dyskinesia: From Dopamine Stabilization to Network Plasticity Modulation

X. Liu, YT. Wang, JQ. Fan, MY. Yan, YX. Wu, SM. Lin, YF. Zhang, LX. Zhuang (Guangzhou, China)

Multisite high-definition gamma-tACS combined with rhythmic auditory cued gait enhances network efficiency in patients with Parkinson’s disease

L. Avanzino, A. Botta, V. Romano, J. Nonnekes, M. Gilat, I. Maidan, A. Mirelman, E. Pelosin (Genoa, Italy)

NIH Multicenter Consortium for Gut-Brain Communication in Parkinson’s Disease: The Master Protocol and Timeline

T. Xie, C. Goetz, L. Becker, A. Bharucha, E. Chang, A. Keshavarzian, B. Kuo, L. Newby, K. Poston, L. Sanders, R. Savica, A. Sharma, A. Videnovic, L. Wruck (Palo Alto, USA)

Preserved Neuroplasticity in Patients Affected by Parkinson’s Disease Responders to External Auditory Cueing Strategies

A. Botta, V. Romano, J. Nonnekes, M. Gilat, A. Mirelman, E. Pelosin, L. Avanzino (Genoa, Italy)

Reduced Cholinergic Activity and Electrophysiological Slowing in Patients with GBA-PD

I. Maidan, M. Bouter, A. Mirelman, G. Bonassi, E. Pelosin, L. Avanzino (Tel Aviv, Israel)

Role of ApoE in α-Synuclein Pathology

A. Jaafar, E. Sierecki (Sydney, Australia)

Sleep Slow-Wave Activity Topography and Dynamics in PD: Relationships with Resting-State fMRI data and Glymphatic Clearance

O. Alenikova, O. Zmachinskaya, M. Dymkovskaya, E. Mykitchuk (Minsk, Belarus)

Subthalamic low-frequency activity reflects engagement during live sports viewing

S. Falciglia, L. Caffi, F. Luiso, C. Palmisano, A. Mazzoni, I. Isaias (Pontedera, Italy)

The Influence of Glymphatic System Impairment on Cognitive Decline in Parkinson’s Disease

Q. Zhang, FT. Liu, J. Wang (Shanghai, China)

The Protective role of Blood brain barrier-Vagal Interface in Parkinsonian pathology in mice

J. Ahn, J. Heo, M. Lee, C. Pyo, J. Jeong, Y. Kim, W. Chung, E. Oh (Daejeon, Republic of Korea)

The Shape Of Sequence Effect In Parkinson’s Disease

A. Grandolfo, L. Angelini, M. de Riggi, D. Birreci, S. Aloisio, G. Paparella, A. Cannavacciuolo, M. Bologna (Rome, Italy)

Transcutaneous Auricular Vagus Nerve Stimulation as a Novel Therapy for Parkinson’s Disease: Meta-Analytic Evidence of Motor and Gait Effects

K. Sarhan (Mansoura, Egypt)

VPS13C Heterozygous Variant as a Potential Modifier in AARS1-Related Charcot-Marie-Tooth Disease with Parkinson’s Disease

C. Ying, X. Zheng, Z. Cen, W. Luo (Hangzhou, China)