Cholinergic Nucleus 4 Degeneration and Cognitive Impairment in REM Sleep Behavior Disorder
Objective: To determine if there is evidence of cholinergic basal forebrain degeneration, i.e., reduced cholinergic nucleus 4 (Ch4) volume on MRI, in patients with REM…Exploring the impact of central cholinergic dysfunction on cognitive functioning in patients of Parkinson’s disease with and without REM sleep behavior disorder
Objective: This paper aims at establishes the presence of significantly higher cholinergic dysfunction in patients using short latency afferent inhibition. Background: Parkinson's disease (PD) is…Relationship between cholinergic basal forebrain volume and short-latency sensory afferent inhibition in Parkinson’s disease with varying degrees of cognitive performance
Objective: To assess the relationship between volumetric measures of cholinergic basal forebrain (CBF) degeneration and short-latency sensory afferent inhibition (SAI) in Parkinson’s disease (PD). Background:…Short-latency afferent inhibition for the assessment of cholinergic degeneration in Parkinson’s disease
Objective: Our objective is to assess how well short-latency afferent inhibition (SAI) represents cortical cholinergic system integrity in patients with Parkinson’s disease (PD), using cholinergic…Parkinson’s disease and nucleus basalis of Meynert integrity: Cognition and everyday function
Objective: To examine the association between the integrity of the nucleus basalis of Meynert (NBM), cognition and everyday function in Parkinson’s disease (PD). Background: Most…The distinctive functional connectivity of the cholinergic nucleus basalis of Meynert in Parkinson’s disease across different motor subtypes
Objective: We aim to compare the state of cortical-NBM functional connectivity across healthy control (HC), PIGD-predominant PD (PIGD-PD), and tremor-dominant PD (TD-PD). Additionally, the correlation…Cholinergic Innervation and Cognitive Functioning in De Novo Parkinson’s Patients with GBA Variations
Objective: To explore the regional cholinergic innervation and clinical characteristics of de novo Parkinson’s disease (PD) patients carrying GBA variants. Background: The most common genetic…In-vivo cholinergic basal forebrain degeneration and cognition in Parkinson’s disease: imaging results from the COPPADIS study
Objective: To assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in a well-characterized multicentric cohort of Parkinson’s disease (PD)…Compared the effects of probiotics and Anti-PD particles on the behavior of Parkinson’s disease mice model
Objective: To compared the effects of probiotics and Anti-PD particles on the behavior of mice with MPTP Parkinson's disease (PD) model. Background: Intestinal flora may…Decreased Regional Cholinergic Signaling in Parkinson’s Disease
Objective: To identify regions of decreased cholinergic signaling in Parkinson's disease (PD) participants relative to cognitively normal controls as measured by positron emission tomography imaging…
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