Deceleration capacity of heart rate: is cardiac vagal modulation impaired in idiopathic Parkinson’s disease?
Objective: Assessment of cardiac vagal modulation through the analysis of heart rate deceleration capacity (DC) in idiopathic Parkinson’s disease (PD). Background: Cardiac autonomic dysfunction manifests…The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients
Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…Meta-Analysis of Short-afferent inhibition and Cognitive Impairment in Parkinson’s Disease
Objective: In this meta-analysis, we assess whether short-afferent inhibition (SAI) is impaired in Parkinson's disease (PD) patients as well as identify clinical variables associated to…Turning during gait is associated with gray matter density of the nucleus basalis of Meynert in Parkinson’s disease
Objective: To examine whether turning during gait is associated with gray matter (GM) density of the nucleus basalis of Meynert (nbM) and attention in people…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…Listen to the heart: Do loud vagal rhythms disharmonize the autonomic symphony in Parkinson’s disease patients with the LRRK2 mutation?
Objective: Assessment of cardiac autonomic function through standard and novel features of heart rate variability (HRV) in individuals who carry the G2019S mutation in the…The correlation studies between cholinergic cognitive impairment of Parkinson’s disease and the cortex thickness of brain
Objective: To determine whether cognitive domain impairment of visuospatial, memory, attention is related to dysfunction of brain cholinergic neurotransmitter system in mild cognitive impairment of…The possible neuroprotective potential of galantamine along with soya-lecithin and hydroxychloroquine against ICV-STZ induced cognitive dysfunction in rats
Objective: The present study investigates the possible neuroprotective potential of galantamine with soya-lecithin and HCQ against intracerebroventricular streptozotocin (ICV-STZ) induced memory impairment in a rat…Fasciculations from a cholinesterase inhibitor
Objective: Present and discuss fasciculations in the setting of acetylcholinesterase inhibitors. Background: Specific acetylcholinesterase (AChE) inhibitors (e.g., donepezil, rivastigmine, galantamine) are the current first-line treatment…Role of Sex on Cholinergic Activity and Attention in Parkinson’s disease
Objective: To determine whether cholinergic activity related to attention differs in males versus females in people with Parkinson’s disease (PwPD). Background: Although cholinergic activity is…
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