Cholinergic Basal Forebrain Atrophy Associates with Short-Latency Afferent Inhibition and Cognitive Impairment in Parkinson’s Disease
Objective: To investigate whether cholinergic basal forebrain (cBF) atrophy mediates the relationship between short-latency afferent inhibition (SAI) and cognitive performance in PD. Background: Cognitive impairment…Neuropsychiatric Symptom Changes in Parkinson’s Disease Patients Treated with Different Doses of Donepezil: A 24-Week Follow-up Study
Objective: This study analyzed the effectiveness of donepezil therapy on neuropsychiatric symptoms in Parkinson’s disease with cognitive impairment (PD-CI), depending on the dose administered. Background:…Coupling of Cholinergic and Dopaminergic Terminal Loss in Progressive Supranuclear Palsy: A Multimodal [18F]FEOBV and [11C]PE2I Study
Objective: To describe the relationships between dopaminergic and cholinergic terminal deficits in Progressive Supranuclear Palsy (PSP) relative to age-matched Normal controls (NC). Background: There is…Cholinergic Systems Changes Associated with Freezing of Gait in Progressive Supranuclear Palsy
Objective: To investigate whether distinctive cholinergic system changes are associated with FoG in PSP patients. Background: Freezing of gait (FoG) is a profound mobility disturbance…Cholinergic Dysconnectivity in Early Parkinson’s Disease Aligns with the Basal Forebrain Functional Gradient
Objective: To determine whether alterations in cholinergic functional connectivity (FC) in early PD relate to the intrinsic organization of the basal forebrain (BF) functional connectome.…Pesticide Exposure and Motor Severity in Parkinson’s Disease in a Mexican Population: A Retrospective Longitudinal Cohort Study
Objective: To evaluate whether pesticide exposure is associated with greater baseline motor severity and accelerated longitudinal motor progression in Mexican patients with Parkinson’s disease (PD).…Brain Cholinergic Changes in Progressive supranuclear palsy: A single-subject voxel-wise approach to understanding heterogeneity
Objective: To characterize individual-level topographical patterns of cholinergic changes compared to controls in Progressive Supranuclear Palsy (PSP) using a voxel-wise approach. Background: The cholinergic system…Topographical heterogeneity of cholinergic system status in Multiple System Atrophy: A series report
Objective: To characterize individual-level topographical patterns of cholinergic upregulation and downregulation in Multiple System Atrophy (MSA) using a whole brain voxel-wise approach. Background: MSA is…Case report and Literature Review on Atypical Parkinson’s Disease
Objective: Atypical parkinsonism is classified as a subgroup of Progressive neurodegenerative diseases, characterized by symptoms of Parkinson's disease. Background: Progressive supra nuclear palsy of the…The Cholinergic System in Cervical Dystonia – An [18F]-FEOBV PET study
Objective: To investigate presynaptic cholinergic functioning in cervical dystonia (CD) by comparing [18F]-FEOBV binding in patients and controls, as well as exploring correlations with motor…
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