A case of donepezil-induced multifocal myoclonus
Objective: To describe the case of a patient who developed severe multifocal myoclonus due to donepezil. Background: Donepezil is a cholinesterase inhibitor frequently used to…Low doses of scopolamine exacerbates dementia among Drosophila with Parkinson’s disease pathophysiology
Objective: To assess the non-inducing doses of scopolamine (SCL) on the memory function of Drosophila previously induced with Parkinson's disease phenotype. Background: A large body…The interplay between cholinergic activity, attention, and turning in Parkinson’s disease
Objective: Explore how cholinergic activity (measured by short latency afferent inhibition [SAI]) and attention relate to quality of turning performance over a week of daily…Deceleration capacity of heart rate: is cardiac vagal modulation impaired in idiopathic Parkinson’s disease?
Objective: Assessment of cardiac vagal modulation through the analysis of heart rate deceleration capacity (DC) in idiopathic Parkinson’s disease (PD). Background: Cardiac autonomic dysfunction manifests…The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients
Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…Non-Invasive Vagus Nerve Stimulation: A non-pharmacological approach to target gait impairment in Parkinson’s disease?
Objective: To determine whether single dose non-invasive vagus nerve stimulation (nVNS) enhances gait performance in Parkinson’s (PD). Background: Loss of cholinergic neurons from nucleus basalis…The correlation studies between cholinergic cognitive impairment of Parkinson’s disease and the cortex thickness of brain
Objective: To determine whether cognitive domain impairment of visuospatial, memory, attention is related to dysfunction of brain cholinergic neurotransmitter system in mild cognitive impairment of…The possible neuroprotective potential of galantamine along with soya-lecithin and hydroxychloroquine against ICV-STZ induced cognitive dysfunction in rats
Objective: The present study investigates the possible neuroprotective potential of galantamine with soya-lecithin and HCQ against intracerebroventricular streptozotocin (ICV-STZ) induced memory impairment in a rat…Fasciculations from a cholinesterase inhibitor
Objective: Present and discuss fasciculations in the setting of acetylcholinesterase inhibitors. Background: Specific acetylcholinesterase (AChE) inhibitors (e.g., donepezil, rivastigmine, galantamine) are the current first-line treatment…Role of Sex on Cholinergic Activity and Attention in Parkinson’s disease
Objective: To determine whether cholinergic activity related to attention differs in males versus females in people with Parkinson’s disease (PwPD). Background: Although cholinergic activity is…
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