Role of APOE ε4 status and Sex on Somatosensory Integration and Dual-Task Cost in Parkinson’s disease
Objective: To determine whether ε4 status relates to impaired somatosensory integration deficits in males more than females in people with Parkinson’s disease (PwPD). Background: Previous…A case of donepezil-induced multifocal myoclonus
Objective: To describe the case of a patient who developed severe multifocal myoclonus due to donepezil. Background: Donepezil is a cholinesterase inhibitor frequently used to…Low doses of scopolamine exacerbates dementia among Drosophila with Parkinson’s disease pathophysiology
Objective: To assess the non-inducing doses of scopolamine (SCL) on the memory function of Drosophila previously induced with Parkinson's disease phenotype. Background: A large body…The interplay between cholinergic activity, attention, and turning in Parkinson’s disease
Objective: Explore how cholinergic activity (measured by short latency afferent inhibition [SAI]) and attention relate to quality of turning performance over a week of daily…Deceleration capacity of heart rate: is cardiac vagal modulation impaired in idiopathic Parkinson’s disease?
Objective: Assessment of cardiac vagal modulation through the analysis of heart rate deceleration capacity (DC) in idiopathic Parkinson’s disease (PD). Background: Cardiac autonomic dysfunction manifests…The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients
Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…Meta-Analysis of Short-afferent inhibition and Cognitive Impairment in Parkinson’s Disease
Objective: In this meta-analysis, we assess whether short-afferent inhibition (SAI) is impaired in Parkinson's disease (PD) patients as well as identify clinical variables associated to…Turning during gait is associated with gray matter density of the nucleus basalis of Meynert in Parkinson’s disease
Objective: To examine whether turning during gait is associated with gray matter (GM) density of the nucleus basalis of Meynert (nbM) and attention in people…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…Listen to the heart: Do loud vagal rhythms disharmonize the autonomic symphony in Parkinson’s disease patients with the LRRK2 mutation?
Objective: Assessment of cardiac autonomic function through standard and novel features of heart rate variability (HRV) in individuals who carry the G2019S mutation in the…
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