Apathy in Parkinson’s disease: Relation to autonomic symptoms
Objective: Our overall goal was to learn whether apathy would be associated with autonomic symptoms in Parkinson’s disease (PD). We examined whether a) PD patients…Temporal dynamics and longitudinal predictors of apathy in Parkinson’s disease
Objective: To determine how apathy varies across different disease stages of Parkinson’s disease (PD) and the longitudinal predictors of its development, using a large PD…Childhood Trauma and Parkinson’s Disease: Associations of Adverse Childhood Experiences, Disease Severity and Quality of Life
Objective: Objective: The goal of this study was to survey individuals with PD to evaluate whether intensity of childhood trauma is associated with individual symptoms,…Neuroanatomical underpinnings of apathy in Parkinson’s Disease
Objective: To investigated the integrity of white matter tracts within basal ganglia-frontal networks in PD patients with and without apathy, and relate these to specific…Neural and cognitive correlates of the co-occurrence of apathy and Impulse Control Disorder in early Parkinson’s Disease
Objective: The present study aims to explore the co-occurrence of impulse control disorder (ICD) and apathy and its neural correlates analyzing anatomical changes in gray…A randomized clinical trial (RCT) to evaluate the effects of safinamide on apathetic non-demented Parkinson’s disease patients
Objective: To evaluate the safety and effects of add-on safinamide on apathy in patients with Parkinson’s disease (PD). Background: Apathy is highly prevalent and disabling…A double-blind randomized clinical trial to evaluate the effects of Candesartan for Cognitive and Neuropsychiatric Impairment in Parkinson’s Disease
Objective: To explore the feasibility of repurposing candesartan for the treatment of cognitive impairment and neuropsychiatric symptoms in PD. Background: There is an urgent need…Ocular ping pong movement to disentangle apathy from Bradykinesia in Parkinson’s disease
Objective: To disentangle bradykinesia from apathy through analysis of ocular movements. Background: While Parkinson's disease (PD) is mainly characterized by motor symptoms such as bradykinesia,…Apathy and Volume of Tissue Activated (VTA) following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Cohort
Objective: To determine frequency and/or predictors of improvement or worsening of apathy, we evaluated this behavior among those who received bilateral subthalamic deep brain stimulation…Apathy in Parkinson’s disease: serum biochemical markers and clinical features
Objective: This study aims to explore clinical features and blood biochemical markers of apathy in PD. Background: Apathy is one of the most common non-motor…
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