Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson’s disease patients
Objective: To study microstructural changes in grey and white matter in early drug-naïve Parkinson's disease (PD) patients and correlate these changes with neuropsychological manifestations. Background:…Tractographically defined subthalamic connectivity is associated with apathy in Parkinson’s disease and healthy subjects
Objective: We aimed to study the baseline white matter characteristics of tractographically defined subthalamic connectivity using Diffusion Tensor Imaging in Parkinson's Disease patients and healthy…Microstructural Changes in Normal Appearing White Matter in Parkinson’s Disease (PD) Correlate with Motor, Tremor, and Neuropsychiatric Scores
Objective: To determine if microstructural changes in the normal appearing white matter of PD are associated with clinical manifestations of disease. Background: White matter (WM)…Distinct effects of apathy and dopamine on effort-based decision making in Parkinson’s disease
Objective: To determine if disrupted effort-based decision making (EBDM) underlies the syndrome of apathy in PD, and whether this disruption is modulated by the dopaminergic…Quality of Life in Parkinson’s Disease: Impact of Depression and Apathy
Objective: The aim of this study is to investigate whether depression and apathy are independently related to QoL in patients with PD. Therefore, we performed…Fatigue and depression are predictors of the tremor form of Parkinson’s disease
Objective: The principal objective is to study the relationship between fatigue and depression with the peculiarities of the progress of PD. Background: Parkinson's disease (PD)…Apathy in Parkinson’s disease is associated with abnormal alpha oscillatory behaviour during incentivized movement
Objective: To determine the relation between apathy and neural oscillations in Parkinson’s disease (PD). Background: Apathy in PD, characterized by lack of motivation, is often…Impaired performance on measures of goal-directed behavior are associated with greater caregiver burden in Parkinson’s disease
Objective: To assess the utility of the Philadelphia Apathy Computerized Task (PACT) in measuring goal-directed behavior in Parkinson’s disease (PD). Background: Impairment in goal-directed behavior…The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…Apathy in adolescents with Tourette syndrome (TS), more than a teenager attitude
Objective: To explore the presence of apathy in teenagers with TS. Background: TS is a complex neuropsychiatric disorder generally classified as a hyperkinetic disorder. Apathy…
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