Can deep brain stimulation implantation cause multiple system atrophy? A retrospective review of MSA patients
Objective: To evaluate whether implantation of deep brain stimulation (DBS) could lead to multiple system atrophy (MSA). Background: Recent studies regarding the transmissibility of alpha-synuclein…Systematic literature review of droxidopa in clinical trials for neurogenic orthostatic hypotension (nOH) in parkinsonism
Objective: The aim of this study was to review the published evidence for the efficacy, safety, and dosing practices of droxidopa treatment for symptomatic neurogenic…The influences of STN-DBS and levodopa on cardiovascular autonomic function in patients with Parkinson’s disease: Evaluated by trigonometric regressive spectral analysis
Objective: To explore the effects of STN-DBS and levodopa on cardiovascular autonomic function in PD. Background: Cardiovascular autonomic dysfunction has been shown in patients with…Alpha-synuclein aggregates of cardiac sympathetic nerves in synucleinopathies and in neurologically unimpaired subjects. Correlation with sympathetic denervation
Objective: To study the cardiac sympathetic innervation and its relationship with the incidence of alpha-synuclein deposits in heart tissue of synucleinopathies and asymptomatic control patients.…Are inflammatory bowel disease and/or treatment with aminosalicylates protective factors against Parkinson’s disease?
Objective: To analyze the association between aminosalicylate-treated inflammatory bowel disease (IBD-A) and Parkinson´s disease (PD) at population level. Background: According to the dual-hit hypothesis, the…Differences of gut bacterial community relate to pathology progress in Parkinson’s disease
Objective: The aim of this study is to examine whether intestinal microbiota correlate with progression of clinical severity and serum inflammation marker. Background: Constipation is…Correlation analysis for postural instability and autonomic dysfunction in patients with Parkinson’s disease
Objective: To investigate correlation between postural instability and autonomic dysfunction in early stage Parkinson's disease patients. Background: Brainstem pathology may link postural instability (PI) and…The relationship among clinical features, DAT scintigraphy and MIBG cardiac scintigraphy in patients with Parkinson’s disease
Objective: The aim of this study is to evaluate correlations among clinical features of Parkinson's disease (PD), odor stick identification test for Japanese (OSIT-J) score,…Assessment of brainstem function with blink reflex variations in Parkinson’s disease
Objective: To assess the brainstem function with different variations of blink reflex studies in Parkinson's disease (PD). Background: Although PD presents principally as a movement…Relationship of muscular strength with cardiovascular function in Parkinson’s disease
Objective: Therefore, the current study examined handgrip strength (Hgs), systolic (SBP) and diastolic (DBP) BP, pulse (PP), and mean arterial pressure (MAP), and rate pressure…
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