Assessment of brainstem function with blink reflex variations in Parkinson’s disease
Objective: To assess the brainstem function with different variations of blink reflex studies in Parkinson's disease (PD). Background: Although PD presents principally as a movement…The relationship among clinical features, DAT scintigraphy and MIBG cardiac scintigraphy in patients with Parkinson’s disease
Objective: The aim of this study is to evaluate correlations among clinical features of Parkinson's disease (PD), odor stick identification test for Japanese (OSIT-J) score,…Correlation analysis for postural instability and autonomic dysfunction in patients with Parkinson’s disease
Objective: To investigate correlation between postural instability and autonomic dysfunction in early stage Parkinson's disease patients. Background: Brainstem pathology may link postural instability (PI) and…Differences of gut bacterial community relate to pathology progress in Parkinson’s disease
Objective: The aim of this study is to examine whether intestinal microbiota correlate with progression of clinical severity and serum inflammation marker. Background: Constipation is…Are inflammatory bowel disease and/or treatment with aminosalicylates protective factors against Parkinson’s disease?
Objective: To analyze the association between aminosalicylate-treated inflammatory bowel disease (IBD-A) and Parkinson´s disease (PD) at population level. Background: According to the dual-hit hypothesis, the…Alpha-synuclein aggregates of cardiac sympathetic nerves in synucleinopathies and in neurologically unimpaired subjects. Correlation with sympathetic denervation
Objective: To study the cardiac sympathetic innervation and its relationship with the incidence of alpha-synuclein deposits in heart tissue of synucleinopathies and asymptomatic control patients.…The influences of STN-DBS and levodopa on cardiovascular autonomic function in patients with Parkinson’s disease: Evaluated by trigonometric regressive spectral analysis
Objective: To explore the effects of STN-DBS and levodopa on cardiovascular autonomic function in PD. Background: Cardiovascular autonomic dysfunction has been shown in patients with…Systematic literature review of droxidopa in clinical trials for neurogenic orthostatic hypotension (nOH) in parkinsonism
Objective: The aim of this study was to review the published evidence for the efficacy, safety, and dosing practices of droxidopa treatment for symptomatic neurogenic…Can deep brain stimulation implantation cause multiple system atrophy? A retrospective review of MSA patients
Objective: To evaluate whether implantation of deep brain stimulation (DBS) could lead to multiple system atrophy (MSA). Background: Recent studies regarding the transmissibility of alpha-synuclein…ECG-based cardiopulmonary coupling for sleep stability assessment in patients with amyotrophic lateral sclerosis
Objective: The goal of this preliminary study is to introduce the technique of CardioPulmonary Coupling (CPC) to visualize and quantify the sleep spectrograms of Amyotrophic…