Characterization of the gastrointestinal dysfunction in the 6-hydroxydopamine rat model of Parkinson’s disease
Objective: To characterize the gastrointestinal (GI) phenotype in the 6-hydroxydopamine (6OHDA) rat model of Parkinson’s disease (PD). Background: GI dysfunction, such as prolonged GI transit…Long-term changes in myocardial sympathetic innervation and function in synucleinopathies
Objective: Describe long-term trends in indices of cardiac sympathetic innervation and function in synucleinopathies. Background: A group of neurodegenerative diseases including Parkinson disease (PD), pure…Is Heart Rate variability a differential biomarker in REM sleep behavior disorder, Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy?
Objective: Heart rate deceleration capacity (DC) and heart rate variability index (HRVI) as potential biomarkers for autonomic dysregulation were studied in subjects (each group N=10)…Degeneration of vagus nerve but not of accessory and phrenic nerve in Parkinson’s disease revealed by high-resolution ultrasound
Objective: To test the hypothesis that the vagus nerve is measurably atrophic in idiopathic Parkinson’s disease (PD). Background: The vagus nerve is discussed to represent…Are Lewy bodies associated with sympathetic pathology in dementia subjects?
Objective: Determine if Alzheimer disease (AD) subjects with Lewy bodies show sympathetic cardiac denervation. Background: Comorbid Lewy body (LB) pathology is very common in AD,…Cardiac sympathetic denervation can predict the wearing-off phenomenon in patients with Parkinson’s disease
Objective: To investigate whether cardiac sympathetic denervation increases the risk of the early wearing-off phenomenon in Parkinson's disease (PD). Background: Recent studies have suggested that…Heart rate variability and Sympathetic skin response in Parkinson’s disease
Objective: To assess the neurophysiologic cardiac autonomic findings and Sympathetic skin response (SSR) in a Tunisian cohort of Parkinson's disease (PD). Background: Prevalence of dysautonomia…Autonomic Dysfunction in Parkinson’s Disease: Role of New Surrogate Markers
Objective: The physiology of respiration is modulated by autonomic efferent neurons and circulating hormones. A continuous ambulatory monitoring of various respiratory parameters helps in early…Proteomic analysis of tear-fluid reveals disease-specific patterns in patients with Parkinson’s Disease
Objective: In this study, we set out to analyse changes of tear fluid (TF) proteome in Parkinson's Disease (PD) patients compared to age-matched controls (AMC)…Gastrointestinal Symptoms and Enteric Nerve Dysfunction in A53T Mice
Objective: To investigate the relationship between α synucleinopathy-induced enteric neuropathy and gastrointestinal dysfunction in A53T mice. Background: Approximately 80-90% of PD patients suffer from GI…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.