Cognitive Reserve and Motor Subtypes of Parkinson’s Disease
Objective: To assess differences in cognitive reserve (CR) between motor subtypes of patients with Parkinson’s disease (PD). Background: Motor subtypes in patients with PD have…A Phase 2 Randomized Clinical Trial of TAK-071, an Acetylcholine M1 Receptor Positive Allosteric Modulator, in Parkinson Disease with Cognitive Impairment
Objective: To study the safety and efficacy of TAK-071, an M1 positive allosteric modulator, in adults with Parkinson disease (PD) with increased risk for falls…The 2-Minute Walking Test Predicts Aerobic Fitness, Motor Function, and Brain Health in Parkinson’s Disease
Objective: To determine the association of performance on the 2-Minute Walking Test (2MWT) with aerobic fitness, motor and cognitive function, and brain health in mild…Assessing Executive Function in HD: Comparing the One Touch Stockings of Cambridge and Zindametrix’s Tower-Z as Components of the HD-CAB
Objective: To assess the comparability of performance by people with Huntington’s disease (HD) on two tower tasks. Background: Cognitive decline is a hallmark feature of…Dual-Task Cost of Walking While Using a Smartphone: A Comparison Study of Older Adults with and Without Cognitive Decline
Objective: To investigate spatiotemporal gait parameters in older adults with and without cognitive decline while walking in the presence of smartphone use. Background: The use…The Cats-and-Dogs Test Predicts Cognitive Impairment in Parkinson’s Disease in a Diverse Population
Objective: To establish whether a visuoperceptual tool (the Cats-and-Dogs test) can predict cognitive impairment (CI) in people with Parkinson’s disease (PwP) in a diverse population.…Misdiagnosis of Cognitive Impairment in Parkinson’s disease
Objective: We explored potential bias to diagnose cognitive impairment in People with Parkinson’s (PwP) followed in the Parkinson’s Progressive Markers Initiative (PPMI). Background: In primary…Subtyping Parkinson’s Disease Mild Cognitive Impairment (PD-MCI) by Cholinergic Degeneration
Objective: This study aims to investigate whether PD-MCI patients exhibiting cholinergic degeneration, evidenced by reduced Ch4 grey matter density (GMD) on brain MRIs, constitute a…Integrated Clinical Research Intern Program: Impact Upon Recruitment of Participants for Therapeutic Studies Aimed at Parkinson’s Disease (PD) Prevention.
Objective: To discuss the development and benefit of an online internship program created to expand recruitment and retention within a PD cohort and introduce students…Cholinergic Basal Forebrain Integrity and Cognition in Parkinson’s Disease
Objective: To examine the association between the integrity of the cholinergic basal forebrain (cBF) and cognition in Parkinson’s disease (PD). Background: Most PD patients experience…
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