White matter and cognition in Parkinson’s disease
Objective: Examine whether a recently developed MRI biomarker intended to assess cerebrovascular small vessel disease, peak width of skeletonized mean diffusivity (PSMD)[1], predicts cognitive decline…Altered functional connectivity of the hippocampus in posterior-cortical subtype of cognitive impairment in Parkinson’s disease
Objective: We aimed to delineate the dual syndrome subtypes of PD-MCI using a data-driven approach and explore hippocampal functional connectivity of the posterior-cortical syndrome. Background:…Subthalamic nucleus deep brain stimulation implant hemisphere differentially changes verbal fluency in patients with Parkinson disease
Objective: To investigate verbal fluency following unilateral subthalamic nucleus (STN) deep brain stimulation (DBS) in patients with Parkinson’s disease (PD). Background: Verbal fluency declines in…Depression in Patients with Parkinson’s disease among Tomsk population
Objective: To identify clinical predictors of depression in Tomsk PwPD. Background: Depression is often an under-recognized feature of Parkinson's disease (PD). It is important to…Effects of white matter hyperintensities, neuropsychiatric symptoms, and cognition on activities of daily living: Differences between Dementia with Lewy Bodies and Alzheimer’s disease
Objective: To investigate if White matter hyperintensities (WMHs), neuropsychiatric symptoms and cognitive performance associate with, and/or predict activities of daily living (ADLs) differently in Alzheimer’s…Initial longitudinal analyses of objectively assessed cognitive functional abilities in a cohort with Parkinson’s disease
Objective: Detect the earliest changes in cognitively demanding activities of daily living in Parkinson's disease (PD) and determine their relationship with changes in global cognition…The Functional Impact of REM Sleep Behavior Disorder in Parkinson’s Disease with Mild Cognitive Impairment
Objective: This study examines whether severity and the functional impact of cognitive decline in Parkinson’s disease mild cognitive impairment (PD MCI) participants differ between those…Cognition-related functional topographies in Parkinson’s disease: Localized loss of the ventral default mode network
Objective: We sought to determine whether functional network abnormalities seen in patients with Parkinson’s disease (PD) and cognitive decline reflect the loss of the default…Combined effects of GBA mutations and STN-DBS negatively impact cognition in Parkinson’s disease
Objective: To compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and non-carriers with and without subthalamic nucleus deep brain stimulation (STN-DBS)…Morbidity and mortality from neurodegenerative patients hospitalized with COVID-19 in the Chicagoland area
Objective: To assess morbidity and mortality of acute COVID-19 infection in hospitalized patients with neurodegenerative diseases and compare with age-matched controls. Background: Outcomes from COVID-19…
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