Oxysterol and chitotriosidase as biomarkers for atypical Parkinsonian symptoms?
Objective: The aim of the study is to establish chitotriosidase and oxysterols as a biomarker for atypical Parkinsonian syndromes in order to make a distinction…Subjective report does not predict objective swallow impairment in atypical Parkinsonian syndromes
Objective: Swallow and speech disturbances are common in patients with atypical parkinsonism. The emergence of swallowing problems, or dysphagia, is associated with increased morbidity and…Clinical predictors of progressive supranuclear palsy (PSP) pathology in PSP syndrome
Objective: To elucidate specific clinical features of progressive supranuclear palsy (PSP) pathology in PSP syndrome. Background: PSP syndrome (PSPS) is the clinical hallmark of PSP;…Atypical Parkinsonian disorders: Insights for a differential diagnosis through the analysis of oculomotor profile in MSA, PSP and CBD patients
Objective: To determine peculiar changes in oculomotor profile that may help in distinguishing atypical parkinsonism with overlapping clinical features. Background: Atypical Parkinsonian disorders (APDs) include…Defining the pathology underlying cortico-basal syndrome: A European study
Objective: To understand how clinical and biological features can help us define and explain the varying pathology that underlies corticobasal syndrome (CBS). Background: Corticobasal degeneration…Prevalence and incidence of PSP and CBS: A new prospective study in the UK
Objective: To estimate the prevalence and incidence of progressive supranuclear palsy (PSP, 'Richardson's syndrome') and corticobasal syndromes (CBS); in the context of all clinical phenotypes…Clinicopathological characteristics of co-existant Parkinson’s disease and corticobasal degeneration: A case study
Objective: Parkinsonism is characterized by bradykinesia, rigidity, rest tremor, and postural instability. The most common cause of parkinsonism is Parkinson's disease (PD) and, rarely, Parkinson-plus…"Atypical" atypical parkinsonism
Objective: To look for additional “atypical“ features in a cohort of patients with a referring diagnosis of a certain atypical parkinsonism using the current diagnostic…Theta burst repetitive transcranial magnetic stimulation in a case with cortical-basal ganglionic degeneration
Objective: Corticobasal ganglionic degeneration (CBGD) is a progressive taupathy involving frontal and parietal cortices as well as basal ganglia. The disease is clinically characterized by…PROSPECT: A UK-based longitudinal observational study of PSP, CBD, MSA and atypical parkinsonism syndromes
Objective: To aid the development of curative treatments, we need to develop better methods for diagnosing Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD) and Multiple…
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