Language impairment in Corticobasal Syndrome: from clinical phenotype to biomarkers
Objective: To investigate the language impairment profile of patients diagnosed as probable Corticobasal Syndrome (CBS) [1] in light of a multimodal imaging biomarkers analysis, namely…Automated Midbrain-Pons Ratio using Artificial Intelligence Differentiates PSP from other Atypical Parkinsonian Disorders
Objective: Our primary goal was to implement an automated measure of the midbrain to pons ratio (MPR) using an artificial intelligence method. Our second objective…The severity and distribution of tau pathology distinguish corticobasal degeneration and progressive supranuclear palsy
Objective: To elucidate whether the severity and distribution of tau pathology reflect the clinical presentations in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Background:…FDG-PET degeneration patterns predict amyloid deposition in Corticobasal Syndrome
Objective: To investigate if an individual clinically-focused analysis of brain FDG-PET metabolic patterns and a comprehensive neurological evaluation could distinguish Corticobasal Syndrome (CBS) pathological variants…Key neuropathological features separating corticobasal degeneration from other related disorders
Objective: This study investigated the key neuropathological features that could separate corticobasal degeneration (CBD) from related parkinsonian disorders by using a decision tree algorithm. Background:…Clinical features and natural course of corticobasal degeneration and progressive supranuclear palsy presenting as corticobasal syndrome
Objective: To compare clinical features and natural course of corticobasal degeneration (CBD) presenting as corticobasal syndrome (CBD-CBS) and progressive supranuclear palsy presenting as corticobasal syndrome…Glucocerebrosidase activity and atypical parkinsonism: a multi-centre exploratory study
Objective: We aimed to determine the frequency of Glucocerebrosidase (GBA) deficiency (subclinical Gaucher's Disease type 1, GD1) in patients with atypical parkinsonism (AP) with features…Activity of Cerebral Networks, Amyloid and Microglia in Corticobasal Syndrome: the ActiGliA study
Objective: The purpose of this prospective cohort study is to analyse the topographical and temporal relationship between cerebral microglia activity changes, network degeneration and atrophy…Baseline analysis of PROSPECT-M-UK: a longitudinal study of PSP, CBS and MSA
Objective: To complete the baseline analysis of clinical data from the PROSPECT-M-UK study and to assess the impact of applying current MDS PSP diagnostic criteria…Cerebellar involvement in progressive supranuclear palsy and corticobasal degeneration
Objective: To investigate cerebellar involvement in vivo in patients with corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) using [18F]FDG PET. Background: Cerebellar ataxia is…
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