STN-DBS in Parkinson’s disease with early motor complications – A 10 year follow-up
Objective: To investigate long-term outcome of subthalamic stimulation (STN-DBS).in Parkinson's disease (PD) patients with early motor complications. Background: STN-DBS improves motor complications and quality of…The core assessment program for surgical interventional therapies in Parkinson’s disease (CAPSIT-PD): Tolerability of preoperative neuropsychological testing for deep brain stimulation in Parkinson’s disease
Objective: We examined tolerability of preoperative neuropsychological testing (the Core Assessment Program for Surgical Interventional Therapies in Parkinson's disease [CAPSIT-PD] protocol) for DBS. Background: CAPSIT-PD…Strengths and weaknesses of patient-reported outcomes following DBS surgery: Comparing clinician, patient, and caregiver assessments
Objective: Assess the degree of correlation between DBS outcome measures rated by patients, caregivers, and clinicians. Methods: The Clinician Global Impression (CGI) score and two…Morbidity and comorbidity of deep brain stimulation for Parkinson’s disease – A thirteen-years retrospective cohort study
Objective: To assess the surgical morbidity and comorbidity in 140 consecutive patients with various disease entities of movement disorders, epilepsy and obsessive-compulsive disorders that underwent…In vivo validation of a new wireless portable stimulator for chronic deep brain stimulation in freely moving rats
Objective: To develop a new dedicated stimulator, adapted for chronic experiments on rodent models and that mimics the conditions of DBS human therapy: bilateral, current-controlled…How do patients experience deep brain stimulation surgery: A prospective patient satisfaction survey
Objective: To evaluate experience of patients who undergo Deep Brain Stimulation (DBS) surgery for treatment of different movement disorders, using patient survey questionnaires. Background: DBS…Reduction in battery longevity for each subsequent implantable pulse generator (IPG) in patients with Parkinson’s disease (PD) treated with bilateral subthalamic nucleus deep brain stimulation (STN-DBS) may be due to both programming changes and IPG model – a case series
Objective: To determine whether the decrease in longevity following IPG replacement is due to programming changes and whether there is an effect of IPG model.…Results from a double-blind trial of pallidal DBS for Tourette’s syndrome: Are there any predictors of surgery outcome?
Objective: To explore whether individual patient characteristics can indicate response to treatment in a trial of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS)…Objective methods for quantifying the deep brain stimulation (DBS) efficacy in subthalamic-nuclei (STN) neurons with microelectrode recording (MER) technology
Objective: To design a computational modeling to develop a new diagnostic tool for effective neuro-medical-diagnostics for end users, to investigate and evaluate the potential benefits…Three-dimensional cytoarchitecture of the basal ganglia: Clinical applications of a computational pipeline for histology to MRI registration
Objective: Use modified histological techniques and a computational registration pipeline to delineate accurately post-operative 3D basal ganglia anatomy in DBS implants. Background: Stereotaxy is based…
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