Seed amplification assay detects alpha-synuclein in cerebrospinal fluid in pre- and symptomatic autosomal dominant Alzheimer’s disease
Objective: To examine the ability to detect concurrent Lewy Body Disease via Lew Body pathology (LBP) in Autosomal Dominant Alzheimer’s Disease (ADAD) through detection of…Demographic Characteristics of Women with Primary Parkinsonism
Objective: To assess the demographic profile and other health characteristics of women with primary parkinsonism who present to the Texas Medical Center for care. Background:…Efficacy of Stimulant Use for Cognitive Fluctuations in Lewy Body Dementia: A Case Study
Objective: To evaluate the effectiveness of stimulants in reducing cognitive fluctuations in Lewy Body Dementia (LBD). Background: Lewy Body Dementia (LBD) is the 2nd most…Identifying Cut-off Values, Effects of AD Co-pathology, Sex Differences, and Temporal Changes of 123I-FP-CIT SPECT in Autopsy-proven LBD
Objective: We analyzed autopsy-proven Lewy body disease (LBD) and/or Alzheimer’s disease (AD) dementia patients with 123I-FP-CIT SPECT to investigate previously unclarified detailed aspects of 123I-FP-CIT…Stepping backwards to move forward A case study on novel PT interventions for DLB
Objective: Explore the effectiveness of backwards walking and backwards stepping interventions to improve gait stability and balance in persons with Dementia with Lewy Bodies (DLB).…Association of Mitochondrial DNA Haplogroup and pS65-Ub Levels in Lewy Body Disease
Objective: To determine whether specific mitochondrial DNA (mtDNA) haplogroup(s) affect the level of p-S65-Ub as quantitative marker of mitochondrial damage in Lewy Body Disease. Background:…Association of β-Amyloid Load on PET with Cognitive Profiles Across the Lewy Body Diseases Continuum
Objective: To investigate the association between Aβ accumulation and clinical characteristics across the Lewy body disease (LBD) spectrum, with a specific focus on global and…Early changes in the locus coeruleus in mild cognitive impairment with Lewy bodies
Objective: To evaluate NMS signal changes in the locus coeruleus (LC) in mild cognitive impairment with Lewy bodies (MCI-LB) as compared to healthy controls (HC)…Prediction of Time-to-Phenoconversion to Parkinsonism in Idiopathic REM Sleep Behavior Disorder (iRBD)
Objective: To develop a tool for the prediction of time-to-phenoconversion in individuals with iRBD during the prodromal stage of parkinsonism. Background: Parkinson’s disease(PD) and dementia…Common Genetic Variation Associated with Parkinson’s Disease Biological Measures
Objective: To identify common genetic variants associated with biological measures that have been implicated in Parkinson’s disease and related synucleinopathies. Background: Alpha synucleinopathies, mainly including…
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