The cortical thickness signature and future phenoconversion in isolated REM-sleep behavior disorder: a longitudinal analysis
Objective: To develop an imaging biomarker predicting subtype-specific phenoconversion in isolated REM sleep behavior disorder (iRBD), we aim at identifying MRI-driven cortical thickness signature in…Deleterious GRN mutations: a new player in the etiology of Lewy body dementia
Objective: In this study we investigated the association of GRN damaging mutations in the etiology of Lewy body dementia. Background: Lewy body dementia (LBD) is…Visualising cholinergic nerves in dementia with Lewy bodies using PET and FEOBV
Objective: Investigate the cholinergic integrity of the central nervous system in dementia with Lewy bodies using PET and a tracer for the vesicular acetylcholine transporter.…Learning to PERSEVERE: Efficacy and Feasibility of Peer Mentor Support and Caregiver Education in Lewy Body Dementia
Objective: To examine the effects of peer mentoring on caregiving mastery, Lewy Body Dementia (LBD) knowledge, and dementia attitudes among LBD family caregivers. Background: Few…Connectivity of dopaminergic networks in the continuum of Dementia with Lewy Bodies
Objective: To examine local and long-distance dopaminergic changes in prodromal DLB (pDLB) patients in a comparison with matched controls and overt DLB dementia patients. Background:…Analysis of the HLA locus in isolated REM sleep behavior disorder and Lewy body dementia
Objective: To examine genetic association of HLA alleles and amino acid for isolated REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD). We compare…Non-Tremor Motor Dysfunction is Associated with AD Biomarkers in Lewy Body Dementias
Objective: To investigate the clinical influence of Alzheimer’s disease (AD) co-pathology on motor features in Lewy Body Dementia (LBD). Background: There is considerable heterogeneity of…AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease
Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…Elucidating multimodal endophenotypes of APOE-ε4 in α-synucleinopathies
Objective: To systematically identify phenotypes that consistently associate with the ε4-allele of apolipoprotein E (APOE-ε4) in α-synucleinopathies. Background: The APOE-ε4 presents an elevated risk not…Event-related oscillations in patients with Dementia with Lewy Bodies with and without mutations in the GBA gene
Objective: To explore the differences in the structure of event-related oscillations (ERO) elicited by a visual oddball task in Dementia with Lewy bodies (DLB) patients…
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