Modeling Dementia in Patients with Parkinson’s Disease Years After DBS
Objective: The objective of this study is to identify pre-operative cognitive characteristics of patients who are candidates for deep brain stimulation surgery that may contribute…Development of the Lewy Body Dementia Domain Rating Scale (LBD-DRS): A disease-specific outcome measure
Objective: To develop and refine the Lewy Body Dementia Domain Rating Scale (LBD-DRS) as a disease-specific outcome measure tailored to the unique clinical features of…Baseline cerebrospinal levels of p-tau and amyloid beta and striatal dopamine transporter binding predict mild cognitive impairment and dementia diagnosis in Parkinson’s disease
Objective: To assess whether baseline measurements of neuroimaging and biofluid-based biomarkers predict diagnosis of mild cognitive impairment (MCI) and dementia at 5-year follow-up in early…Exploring the Association of APOE Polymorphism and the Clinical Course of CSF1R-Related Disorder
Objective: To assess the frequency of APOE alleles and their association with clinical course of Colony Stimulating Factor 1 Receptor-Related Disorder (CSF1R-RD). Background: CSF1R-RD is…Cognitive Decline in Parkinson’s Disease: A Decade-Long Registry Analysis of Prevalence and Risk Factors
Objective: This study aims to identify predictors of cognitive decline in cognitively normal Parkinson’s disease patients by analyzing the 10 years-long PD registry. Background: Cognitive…Clinical and Pathological Features of CSF1R-Related Disorder Associated with the c.2330G>A, p.R777Q Pathogenic Variant
Objective: To report the clinical and pathological features of CSF1R-RD associated with the c.2330G>A, p.R777Q variant, and to report a new family carrying this variant.…Long-Term Dementia Risk in the General Parkinson Disease Population
Objective: To estimate the long-term risk of developing dementia in the general Parkinson’s disease (PD) population and to assess the influence of age at PD…Gait Analysis and Outcome of CSF Drainage in Patients of Normal Pressure Hydrocephalus
Objective: NPH is a clinical entity causing impairment in gait, bladder and memory functions. Of these, gait dysfunction is the most prominent and disabling as…Co-Occurrence of DAT Scan, Amyloid PET Scan, and Alzheimer’s Genetic Screening Abnormalities in Patient with Early-Onset Neurocognitive Decline: A Case Report
Objective: The presented case report aims to show the possible overlap between causes of neurocognitive decline and the importance of considering comorbidities when discussing anti-amyloid monoclonal…Expanding the Geographic Spectrum of Guam Complex: A Case Report from Colombia
Objective: To describe the case of a patient presenting with a progressive neurodegenerative syndrome characterized by the coexistence of dementia, parkinsonism, and motor neuron disease.…
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