Dopaminergic Modulation Of Contextual Emotional Appraisal And Shame In Parkinson’s Disease
Objective: To investigate the influence of dopaminergic replacement therapy (DRT) on emotional appraisal and shame-related responses in PD patients with fluctuations. Background: Shame and embarrassment…Dopamine depletion does not mitigate striatal reward prediction error signals
Objective: To elucidate the role of dopamine in computing reward prediction error signals in the basal ganglia Background: Phasic discharges of midbrain dopamine neurons are…R1 from 18PR04.MZ as a Proxy for Cerebral Blood Flow in Degenerative Parkinsonism: Comparison with 15O-H2O PET/CT.
Objective: To evaluate the relationship between R1 from 18PR04.MZ and CBF assessed by 15O-H2O PET/CT in patients with parkinsonian syndromes. Background: 18PR04.MZ is an effective…Mathematical and Computational Modeling Prototype to Understand the Evolution of Parkinson’s disease using Four Differential Equations
Objective: Apply four differential equations to generate projections considering the effect of dopamine on Parkinson’s disease progression, leading to the development of an initial prototype…Detection and classification of Parkinson’s disease from neuroimaging modalities using machine learning and artificial intelligence: a systematic review
Objective: This systematic review evaluates performance of machine learning (ML) and artificial intelligence (AI) techniques applied to neuroimaging modalities in differentiating Parkinson’s disease (PD) patients…Dopaminometer: A Smartphone-Based Application to Predict Striatal Dopaminergic Deficit in Prodromal and Manifest Parkinson’s disease
Objective: To assess the feasibility of a smartphone-based application (“Dopaminometer”) for predicting abnormal vs. normal dopamine transporter (DaT) scans and dopaminergic ratios in individuals with…Functional Segregation in Parkinson’s Disease
Objective: We assessed patterns of dopamine (DA) release and striatal activation induced by behavioural tasks involving corticostriatal loops in Parkinson’s disease (PD) and healthy control…Artificial Intelligence in the Early Detection of Parkinson’s Disease: Advances, Challenges, and Future Perspectives
Objective: This study reviews AI’s role in early PD detection, comparing AI-driven diagnostic methods with conventional clinical approaches in accuracy, reliability, and applicability. Background: Parkinson’s…The role of serotonergic mechanisms in the formation of levodopa-induced drug-induced dyskinesias in Parkinson’s disease
Objective: To study the quantitative content of serotonin and dopamine in the blood plasma of patients with Parkinson's disease and to conduct a clinical and…Long-Term Effect of Dopaminergic Treatment on gait in De Novo Parkinson’s Disease: the DNA mobile health technology longitudinal study
Objective: to evaluate the long-term effect of dopaminergic treatment on gait in Parkinson’s disease Background: monitoring the progression of Parkinson's disease (PD) and response to…
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