Gait Imagination and Gait Observation Related Midfrontal Oscillations in People With Parkinson’s Disease and Freezing of Gait
Objective: To examine midfrontal oscillations in people with Parkinson’s disease (PD) with freezing of gait (PDFOG+), without FOG (PDFOG–), and healthy controls during gait imagination…Characterizing the Neural Signature of Parkinsonian Freezing of Gait During an Immersive Virtual Reality Paradigm
Objective: To characterize the neural signature of Freezing of gait (FOG) in Parkinson’s disease (PD) across multiple types of triggers. Background: FOG is among the…The Cleveland Clinic-Virtual Home Environment (CC-VHE): A Reliable Way to Trigger Freezing of Gait in Parkinson’s disease
Objective: To describe the development, safety, and efficacy of the Cleveland Clinic-Virtual Home Environment (CC-VHE) in provoking freezing of gait (FOG) in Parkinson’s disease (PD).…The Impact of Freezing of Gait on Falls over time in Parkinson’s disease
Objective: To quantify falls related to Freezing of Gait (FoG) versus unrelated to FoG as Parkinson’s disease progresses. Background: FoG is a debilitating symptom of…Bassoon (BSN) Gene Mutations: A Missing Link in Gait and Balance Dysfunction Across Parkinsonian Disorders?
Objective: To elucidate the clinical significance of mutations in the Bassoon (BSN) gene in early-onset Parkinson’s disease (PD). Background: PD involves complex motor deficits beyond…Predicting Freezing of Gait (FoG) in Parkinson’s Disease from Conventional T1-Weighted MRI
Objective: To predict freezing of gait in individuals with Parkinson's disease using T1-weighted MRI and machine learning techniques. Background: Freezing-of-gait (FoG) is a debilitating condition…Differences in regional activity levels between healthy controls, PD-nFOG, and PD-FOG as measured by ALFF and fALFF using resting-state fMRI.
Objective: To elucidate regional neural activity differences in patients with PD-FOG using resting-state fMRI (rs-fMRI). Background: Freezing of gait (FOG) in Parkinson's disease (PD0 is…Cardiac Mitochondrial Complex I Integrity Predicts Axial Symptom Severity in Parkinson’s Disease
Objective: In the present work, we investigated whether cardiac mitochondrial dysfunction might also be associated with the severity of PIGD symptoms in PD patients. Background:…Acute and chronic effects of deep brain stimulation on gait in patients with Parkinson’s disease.
Objective: To investigate the acute and chronic effects of deep brain stimulation (DBS) of subthalamic nucleus (STN) or globus pallidus internus (GPi) on gait in…Comparative Analysis of GAITRite and Moticon Digital Insoles for Gait Assessment in Parkinson’s Disease Patients Before and After Levodopa Administration
Objective: Parkinson’s disease (PD) is characterized by gait impairments, impacting patient mobility and quality of life. This study compares a reference gait measurement system, GAITRite (GR) against digital…
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