Identifying the neural correlates of doorway freezing in Parkinson’s disease
Objective: We aimed to combine a previously validated virtual reality gait paradigm with functional Magnetic Resonance Imaging (fMRI) to investigate the neural correlates underlying doorway-provoked…A cortical neural signature of motor interruption in patients with Parkinson’s disease and freezing of gait
Objective: To investigate whether cortical oscillations involved in sensorimotor and perceptual processes [alpha (8-12 Hz), low beta (13-20 Hz) and high beta (21-35 Hz)] change…Frontal-subcortical cognitive impairments in Parkinson’s patients with freezing of gait
Objective: To evaluate the relationship between frontal-subcortical cognitive dysfunctions and freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a complex and multisystem…Determination of falling direction in Parkinson’s disease patients using a wearable sensor
Objective: The aim of this study is to objectively detect falls and their direction in Parkinson’s disease (PD) patients during everyday activities. Background: Falling is…Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations
Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…The Prevalence of Tandem Gait Abnormality in Parkinson’s Disease
Objective: To assess the prevalence of tandem gait abnormality in patients with Parkinson’s disease (PD), comparing Hoehn and Yahr (HY) stages 2 and 3. Background:…Cortical correlates of dual-task turning with and without freezing of gait
Objective: This study investigated the relationship between prefrontal cortex (PFC) activity and turning characteristics with and without a dual-task in in people with Parkinson’s disease…Altered connectivity in ventral and dorsal attentional networks in patients with Parkinson’s disease: Association with freezing of gait
Objective: To examine the changes in connectivity of the attentional networks in Parkinson's disease (PD) and their role in freezing of gait (FOG). Background: Deficits…Gait disturbance and olfactory dysfunction is associated with central cholinergic dysfunction in early Parkinson’s disease
Objective: We hypothesis that olfactory dysfunction, could be an independent predictor of gait disturbance in early PD. Background: The pathophysiology of gait disturbance is not fully…Successful passive monitoring of early-stage Parkinson’s disease patient mobility in Phase I RG7935/PRX002 clinical trial with smartphone sensors
Objective: Smartphone-based assessments and sensors have the potential to enable remote, passive monitoring of gait and mobility in early-stage Parkinson’s disease (PD) patients. Such sensor…
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