The role of intraoperative electrophysiological monitoring in implanting globus pallidus internus electrodes in patients with dystonia
Objective: The first aim was to compare the preplanned GPi electrode neuroradiological trajectory with the final trajectory selected after electrophysiological monitoring. The second aim was…Structural connectivity affecting freezing of gait after globus pallidus internus deep brain stimulation in Parkinson’s disease
Objective: We aim to investigate how structural connectivity of the brain affects gait freezing after globus pallidus internus (GPi) deep brain stimulation (DBS). Background: Freezing…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Pallidal deep brain stimulation entrains finely tuned gamma oscillations in motor cortex
Objective: Determine whether therapeutic pallidal deep brain stimulation can entrain finely tuned gamma oscillations in the motor cortex. Background: In Parkinson’s disease (PD), finely tuned…Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study
Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…Pallidal single unit activity in cervical dystonia patients with unilateral deep brain stimulation
Objective: The aim of the current study is to characterize the neuronal activity of the pallidal area which gives the best benefit following unilateral deep…Pallidal deep brain stimulation alters reward learning in segmental dystonia: a pilot study
Objective: To investigate the effect of pallidal deep brain stimulation (DBS) on reward learning in segmental dystonia. Background: Reversal learning is impaired in patients with…The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…Retrospective Review of Globus Pallidus Deep Brain Stimulation Electrode Contact Locations and Clinical Outcomes in Parkinson’s Disease
Objective: To evaluate the location of therapeutic electrode contacts and correlate those with the clinical outcomes of deep brain stimulation (DBS) of the globus pallidus…Increased expression of conexin 36 in rodent model of Parkinson disease
Objective: To evaluate changes in non-synaptic mechanisms associated with the procedures to reproduce the neurophysiological conditions typical of Parkinson's disease (PD). Background: Many mechanisms that…
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