Insulin-like growth factor 2 and inflammatory response in Parkinson Disease: Potential predictor marker
Objective: Clinical diagnosis Parkinson's disease (PD), is often difficult, with the appearance of motor symptoms hence the importance of identify non-invasive early markers is a…Mitigating The Impact Of Covid-19 On Parkinson’s Disease: Insights From Vaccination Strategies
Objective: This study aimed to investigate the impact of COVID-19 infection on patients with Parkinson's disease (PD), comparing those who received COVID-19 vaccines and those…Age and Parkinson’s disease: clinical and biomarkers profiling of younger and older patients
Objective: Given the well-known clinical differences and natural history of Parkinson's disease (PD) according ot patients age, wthis study aims at exploring the different pathophysiological…TRPV1: A Potential Therapeutic Target for Inflammation and Pain in Parkinson’s Disease
Objective: Unveiling the Pain Mechanism in Parkinson's Disease: A Path to New Therapies Background: Parkinson's disease (PD) are well-known movement disorder. While motor symptoms are…Functionality Analysis of Immunoregulatory Cells Stimulated with Dopaminergic Agonists in People Living with Parkinson’s Disease
Objective: To evaluate the effect of dopaminergic agonists (DA) on the activation and functionality of regulatory cells in People living with Parkinson's Disease (PwP). Background:…The effect of Diabetes Mellitus and Cardiovascular disease on Parkinson’s disease
Objective: To understand the impact of the comorbidities; namely Type 2 Diabetes Mellitus (DM) and/or cardiovascular disease (CVD) on the clinical features of Parkinson’s disease…Quantification of Neuroinflammation and White Matter Injury in Parkinson Disease Using Diffusion Basis Spectrum Imaging
Objective: To investigate differences in white matter (WM) using Diffusion Basis Spectrum Imaging (DBSI) between participants with Parkinson’s disease (PD) and controls and to examine…Reduced intestinal inflammation and increased levels of short-chain fatty acids thanks to an active lifestyle in Parkinson’s disease.
Objective: This study aimed to determine whether people with Parkinson’s disease (PD) with an active lifestyle had increased production of certain microbial metabolites such as…Inflammation Biomarkers and Free Water Fraction in the Cholinergic Forebrain System in Idiopathic Parkinson’s Disease
Objective: Investigate if inflammatory biomarkers moderate the association between, cholinergic basal forebrain free water fraction and cholinergic innervation in idiopathic Parkinson’s disease. Background: The cholinergic…The Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons with REM Sleep Behavior Disorder (RBD)
Objective: To explore the potential for an immunologically based intervention to slow evolution of symptoms in persons with prodromal or Stage 2b (Simuni et al.…
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