Formulations and evaluations of Intranasal Nose to Brain Delivery of Curcumin with resveratrol Nanoparticle for treatment of Parkisonism
Objective: Parkinson’s disease (PD) is a common neurodegenerative disease characterized by motor symptoms of tremor, rigidity, bradykinesia, and postural instability. Growing evidence indicates that resveratrol…Association of genetic polymophisms with pharmacokinetics of levodopa in South indian PD patients
Objective: To evaluate the role of COMT gene variations on the pharmacokinetics (PK) of L-dopa in PD patients. Background: Genetic variations in enzymes (MAO-B, COMT),…Parkinson’s disease and melanoma: a serie of 33 patients
Objective: The objective of our work was to characterize the clinical features of patients with malignant melanoma (MM) associated with Parkinson’s disease (PD) and to…Estimating the long-term effect of early levodopa treatment initiation in Parkinson’s disease
Objective: Using observational longitudinal data to estimate the long-term effect of the duration of levodopa treatment in the first two years after diagnosis. Background: Levodopa…Deep Brain Stimulation as a Rescue When Duodenal Levodopa Infusion Fails: Report of 2 Cases
Objective: To describe two cases of patients with Parkinson’s disease (PD) where deep brain stimulation (DBS) was used a rescue therapy when duodenal levodopa infusion…Design, characterization and In vivo evaluation of intranasal delivery of levodopa loaded microspere for Parkinsonism
Objective: Levodopa is the drug of choice in the treatment of Parkinson's disease but it exhibits low oral bioavailability and very low brain uptake. The…Sudden alopecia secondary to levodopa treatment
Objective: Report a rarely documented side effect of dopaminergic therapy and review the literature on this aspect, highlighting the underlying mechanisms hypothetically involved. Background: Levodopa…Levodopa response in later stages of Parkinson’s disease: a case-control study
Objective: To compare the response of motor and non-motor symptoms (NMS) to a L-dopa challenge test between late stage (LS) PD patients and advanced stage…Factors associated with dyskinesia in Parkinson’s disease in Mainland China
Objective: To identify the association between dyskinesia and related risk factors, the medication dosage range considered safe and treatment-related variables.To identify the association between dyskinesia…Levodopa-responsive tremor in a young child as a delayed complication of osmotic demyelination from severe hypernatremia
Objective: To describe a case of levodopa responsive tremor due to osmotic demyelination as a result of severe hypernatremia Background: Osmotic demyelination is a known…
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