Use of insect model to study Parkinson’s disease pathophysiology by inducing GSH-depletion and behavioral deficits among larvae: Evidences of ameliorative properties of phytoconstituents
Objective: The purpose of the study is to establish an all-around model for Parkinson's disease using Drosophila melanogaster, the fruit-fly in order to understand behavioral…Developing zebrafish CRISPR/Cas9 knockout models of Parkinson’s Disease to identify novel therapeutic targets.
Objective: Human patients present punctual mutations and/or small deletions in genes that have been associated with Parkinson’s disease, namely, park1, park2, park6, park7, and park8.…Long-term wearable tele-rehabilitation of gait for persons with Parkinson’s disease: A feasibility study
Objective: This study aims to evaluate the feasibility of long-term wearable tele-rehabilitation of gait in people with Parkinson’s disease. Background: Tele-rehabilitation allows patients to utilize…Measuring what matters in Parkinson’s disease – validating real-world digital mobility outcomes for widespread adoption
Objective: To validate and support widespread adoption of real-world digital mobility outcomes (DMOs) to monitor mobility performance, disease progression and predict falls in patients with…ADS024 attenuates striatal dopamine loss and restores movement in animal models of Parkinson’s disease
Objective: To evaluate the effect of ADS024, an oral single strain live biotherapeutic product (SS-LBP), on the pathophysiology of MPTP-induced Parkinson’s Disease (PD) phenotypes in…Tremor as a Hallmark of Neurodegeneration and Mercury Intoxication
Objective: The aim of our study was to evaluate a computerized method for assessing tremor in neurodegenerative diseases and toxic effects of mercury, taking into…Detecting Parkinson’s Disease from body limb acceleration using machine learning and a frequency-domain analysis
Objective: To test whether the acceleration frequency of different body parts during gait can reveal characteristic patterns of Parkinson’s Disease (PD). The technical aim was…Gait abnormalities relate to increased extracellular water in the substantia nigra in Parkinson’s disease patients
Objective: The aim of this study was to investigate the role of substantia nigra microstructural integrity in parkinsonian gait impairments. Background: Gait impairments are common…Turning during single and dual tasking in Parkinson’s Disease
Objective: To investigate turning kinematics and intersegmental coordination in single (ST) and dual tasking (DT) in Parkinson’s Disease (PD) patients. Background: Successful turning depends on…Satisfaction Survey on a Parkinson’s Holter, a Medical Device for the Monitoring of Motor Symptoms
Objective: To know the level of satisfaction on a CE Class IIa medical device for monitoring motor symptoms in Parkinson’s Disease (PD). Background: Identifying and…
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