In vitro α–synuclein aggregation and propagation model
Objective: Developing an in vitro α–synuclein (α-s) aggregation and propagation model of human cortical networks for functionality studies. Background: Studying α–s pathology and its effects…AI-Guided Microelectrode Recording for GPi DBS in Parkinson’s disease
Objective: To evaluate the feasibility of using a machine learning algorithm to interpret intraoperative microelectrode recording (MER) during deep brain stimulation (DBS) lead placement surgery.…Electrophysiology marker of levodopa induced dyskinesia in Parkinson disease
Objective: To review various electrophysiology markers of levodopa induced dyskinesia (LID) investigated in current studies and the pathophysiology of LID in the context of abnormal…Pallidal firing rate and alpha oscillations correlate with the severity of clinical symptoms in patients with dystonia
Objective: To examined how pallidal activity correlates with symptom severity across dystonic patients. Background: The internal segment of globus pallidus (GPi) is the most common…Oscillatory activity of pause-burst STN neurons shows an association with motor symptoms of Parkinson’s disease
Objective: Here we aimed to investigate heterogeneity in the neuronal activity within the subthalamic nucleus (STN) to search the association between oscillatory activity and motor…Machine learning supervised classification study for Parkinson`s disease progression through graph-based feature selection method
Objective: The model helps neuro physicians/ neurologists to improve the PD symptoms, or therapeutic-treatment planning-procedures. Background: Artificial intelligence-based machine learning (AI-ML) supervised classification systems have…Specificity of neuronal activity in globus pallidus in patients with DYT1 dystonia
Objective: The aim of this study was a comparative analysis of the neuronal activity of globus pallidus in patients with DYT1 dystonia and idiopathic dystonia.…Intraoperative microelectrode recodings reveal functional structure of Globus Pallidus pars interna in dystonic patients
Objective: We characterized the functional structure of Globus pallidus pars interna (GPi) in dystonic patients by analizing the distribution of the firing pattern features in…Five for the price of one- A multidirectional micro-electrode recordings for DBS Surgery
Objective: To examine the use of a multidirectional micro electrode during Deep Brain Stimulation (DBS) surgery for Parkinson's Disease (PD) in 9 patients. Background: Micro-Electrode…High frequency neck vibration changes the pallidal activity in cervical dystonia
Objective: The aim of the current study is to characterize changes in spontaneous pallidal neuronal activity during modulation of peripheral proprioceptive input by means of…
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