Nicotine and influences on hyperkinetic movement disorders
Objective: We describe hyperkinetic movement disorders with a variable response to smoking and nicotine and review clinical and pre-clinical evidence regarding the role of smoking,…Effects of fine particulate matter and cigarette smoking on MPTP-induced dopaminergic neuronal cell death: Implication for Parkinson’s disease
Objective: The objective of this study was to determine the potential neurotoxicity of fine particulate matter (FPM) and the neuroprotective properties of nicotine in the pathogenesis…Coffee, smoking and aspirin are associated with age at onset and clinical severity in idiopathic Parkinson’s disease
Objective: To investigate a possible association between smoking, the consumption of caffeine and the use of aspirin on age at onset (AAO), motor and non-motor…Is the association between cigarette smoking and Parkinson disease causal? A Mendelian Randomization study.
Objective: To determine whether the association between cigarette smoking and Parkinson disease (PD) is causal using 2-sample Mendelian randomization (MR) and to examine the potential…Preoperative Smoking History Increases Risk of Infection in Deep Brain Stimulation Surgery
Objective: Although general risk of deep brain stimulation (DBS) therapy has been previously described, application of risk prediction at the individual patient level is still…The NIC-PD-study –A randomized, placebo-controlled, double-blind, multi-centre trial to assess the disease-modifying potential of transdermal nicotine in early Parkinson‘s disease in Germany and N. America
Objective: To evaluate the disease modifying potential of transdermal (TD) nicotine in early Parkinson’s disease (PD). For this explanatory purpose, the primary endpoint was the…Effects of JN403, an α-7-nicotine-acetylcholine-receptor (α7-nAChR) agonist on human alpha-synuclein-mediated in vitro and in vivo models of Parkinson’s disease
Objective: To investigate whether JN403, a novel selective agonist of α-7-nicotine-acetylcholine-receptors (α7-nAChRs) can suppress inflammation and toxicity in human alpha-synuclein (αSyn) induced in vitro and…The NIC-PD-study –Baseline data of a randomized, placebo-controlled, double-blind, multi-centre trial to assess the disease-modifying potential of transdermal nicotine in early Parkinson’s disease in Germany and the USA
Objective: The primary endpoint of clinical progression is measured by change in the total UPDRS score between baseline and 1) after 52 weeks of study…Moist smokeless tobacco (Snus) use and risk of Parkinson’s disease: Meta-analysis of individual participant data from seven prospective observational studies
Objective: To investigate the associations between use of Swedish moist smokeless tobacco (snus) and risk of Parkinson's disease (PD). Background: Cigarette smoking is associated with…Headache in patients with Parkinsons disease: Pilot study results
Objective: Investigate the prevalence and characteristics of headache in PD patients, acknowledge the existing relation within the predominant laterality of the headache and side of…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.