Effects of JN403, an α-7-nicotine-acetylcholine-receptor (α7-nAChR) agonist on human alpha-synuclein-mediated in vitro and in vivo models of Parkinson’s disease
Objective: To investigate whether JN403, a novel selective agonist of α-7-nicotine-acetylcholine-receptors (α7-nAChRs) can suppress inflammation and toxicity in human alpha-synuclein (αSyn) induced in vitro and…Headache in patients with Parkinsons disease: Pilot study results
Objective: Investigate the prevalence and characteristics of headache in PD patients, acknowledge the existing relation within the predominant laterality of the headache and side of…Moist smokeless tobacco (Snus) use and risk of Parkinson’s disease: Meta-analysis of individual participant data from seven prospective observational studies
Objective: To investigate the associations between use of Swedish moist smokeless tobacco (snus) and risk of Parkinson's disease (PD). Background: Cigarette smoking is associated with…The NIC-PD-study –Baseline data of a randomized, placebo-controlled, double-blind, multi-centre trial to assess the disease-modifying potential of transdermal nicotine in early Parkinson’s disease in Germany and the USA
Objective: The primary endpoint of clinical progression is measured by change in the total UPDRS score between baseline and 1) after 52 weeks of study…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.