Is DAT imaging abnormality in Normal Pressure Hydrocephalus always suggestive of degeneration? Evidences from three cases
Objective: To study parkinsonism in iNPH, in order to shed light on its pathogenesis, understand potential overlap with idiopathic parkinsonismsand its impact on the clinical outcome.…Correlation between cerebral perfusion and striatal dopamine transporter activity by dual SPECT study in Parkinsonian syndromes
Objective: We aimed to investigate the correlations between brain perfusion and striatal dopamine transporter (DAT) activity in parkinsonian syndromes and to characterize the difference in…Effect of striatal dopamine depletion on cognition in de novo Parkinson’s disease
Objective: To investigate the relationship between the sub-regional pattern of striatal dopamine depletion and cognitive impairment in early-stage Parkinson’s disease (PD), and determine the effect…Non-Progressive Coreoatethosis Secondary to Infantile Necrotizing Encephalopathy Mimicking Leigh Disease.
Objective: Our objective is to report image findings of an acute necrotizing encephalopathy of childhood (ANEC) in a 15 years-old girl, completely normal until 18…Correlation analysis between dopamine release in striatal sub-regions and motor impairment in Parkinson’s disease subjects
Objective: To investigate correlations between the sub-regional dopamine release (DR) in the striatum of Parkinson’s disease (PD) subjects and sub-components of motor performance evaluated according…Persistent L-Dopa Responsive Hemiparkinsonism After Cryptococcoal Meningoencephalitis in an Immunocompetent Man
Objective: Our objective is to report a case of persistent L-dopa responsive hemiparkinsonism after Cryptococcal meningoencephalitis in an immunocompetent man. Background: Fungal infections of the CNS are…U-shaped dopamine resting state connectivity response function related to working memory performance in adults with early-stage Parkinson’s disease
Objective: Appraise how cognitive performance and neural response is affected by nigrostriatal denervation in early-stage Parkinson’s disease (PD). Background: Cognitive dysfunction in PD is heterogeneous…99mTc -TRODAT- 1 SPECT SHOWING DOPAMINERGIC DEFICIENCY IN A PATIENT WITH SPINOCEREBELLAR ATAXIA TYPE 10 AND PARKINSONISM.
Objective: In this report, we describe a Brazilian patient with SCA10, with parkinsonism, with a 99Tc - TRODAT-1 SPECT demonstrating dopaminergic deficiency. Background: Spinocerebellar ataxia…Neuroprotective and antidepressant-like effects of the endogenous amines from tetrahydroisoquinoline group TIQ and 1MeTIQ in the animal model of depressive disorder: Behavioral and neurochemical studies in the rat
Objective: For the purpose of estimation neuroprotective and antidepressant-like effects of the endogenous amines 1,2,3,4-tetrahydroisoquinoline (TIQ) and its close methyl derivative, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) in the…Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s disease
Objective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…