Patients with Parkinson’s Disease Share a Unique Olfactory Perceptual Fingerprint
Objective: To explore potential olfactory biomarkers for early detection of Parkinson's disease Background: Although the olfactory decline in Parkinson’s disease (PD) precedes the motor symptoms…Olfactory Network Reorganization in Parkinson’s Disease
Objective: To explore changes in the organization and functionality of the olfactory network in patients with Parkinson’s Disease (PD) using graph theory-based network analysis on…Olfactory dysfunction in patients with Huntington disease
Objective: To investigate olfactory dysfunction (OD) in individuals with Huntington disease (HD) and its relation to disease severity. Background: HD is a hereditary neurodegenerative disease…Melatonin attenuates the bidirectional Gut-Brain axis mediated inflammation caused by Ambient Particulate Matter (PM2.5) and averts neurodegeneration
Objective: To explore the therapeutic potential of melatonin in attenuating the PM2.5 induced inflammation and neurodegeneration through the Gut-brain axis in C57BL/6 mice. Background: The…CORRELATION BETWEEN OLFACTORY DYSFUNCTION AND INTENSITY OF TREMOR
Objective: Our aim was to obtain tremor data of PD and ET patients and the results of their olfactory function, which can help verify our…Extending the spectrum of non-motor symptoms in pre-motor Huntington’s disease – a pilot study
Objective: The aim of this pilot study was to investigate change of olfactory functions in Huntington's disease. Background: Huntington's disease (HD) is a neurodegenerative disease…Defining LRRK2-PD subsets based on olfactory function in the PPMI
Objective: A major goal of the Parkinson Progression Marker Initiative (PPMI) is to identify clinical and biomarker defined disease subsets that may demonstrate differing disease…Serum uric acid as a putative biomarker in Prodromal Parkinson’s disease: Longitudinal data from the PPMI study.
Objective: Our present study assessed the role of serum uric acid as a putative biomarker in a prodromal PD cohort [REM Sleep Behavior disorder (RBD)…Comparisons Between Parkinson’s Disease Patients and At-Risk Individuals: Can Olfactory Deficits and Cognitive Measures Serve as Preclinical Markers?
Objective: To examine whether individuals at increased risk of developing Parkinson’s disease (PD) show specific cognitive impairments suggestive of progression towards PD. Background: Olfactory deficits…Serial DaT-SPECT imaging in asymptomatic carriers of LRRK2 G2019S mutation: 8-years follow-up
Objective: To characterize the 8-year progression of clinical and imaging biomarkers in a cohort of asymptomatic LRRK2 G2019S carriers and to assess its utility as predictors of…
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