BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.
Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…Relationship Between Hyposmia and Olfactory Network Connectivity in Patients With Parkinson’s Disease
Objective: To examine resting-state functional Magnetic Resonance Imaging in a group of Parkinson’s Disease patients, used to characterize changes in functional connectivity of the olfactory…Predictive value of UPSIT subsets in prodromal Parkinson disease
Objective: To assess the predictive value of previously published subsets of the University of Pennsylvania Smell Identification Test (UPSIT) odors for conversion to Parkinson disease…Serial olfactory testing for the diagnosis of prodromal Parkinson disease in the Parkinson Associated Risk Syndrome (PARS) study
Objective: To assess whether repeat olfactory testing in initially hyposmic subjects improves prediction of conversion to Parkinson disease (PD). Background: Hyposmia is a common prodromal…Smell dysfunction correlates with severity of motor deficits in H&Y stage-I early onset Parkinson’s disease
Objective: The objective of this study is to test the hypotheses that: 1) olfactory dysfunction in early stage Parkinson’s disease (PD) is correlated with severity…Extending the spectrum of non-motor symptoms in pre-motor Huntington’s disease – a pilot study
Objective: The aim of this pilot study was to investigate change of olfactory functions in Huntington's disease. Background: Huntington's disease (HD) is a neurodegenerative disease…Defining LRRK2-PD subsets based on olfactory function in the PPMI
Objective: A major goal of the Parkinson Progression Marker Initiative (PPMI) is to identify clinical and biomarker defined disease subsets that may demonstrate differing disease…Serum uric acid as a putative biomarker in Prodromal Parkinson’s disease: Longitudinal data from the PPMI study.
Objective: Our present study assessed the role of serum uric acid as a putative biomarker in a prodromal PD cohort [REM Sleep Behavior disorder (RBD)…Comparisons Between Parkinson’s Disease Patients and At-Risk Individuals: Can Olfactory Deficits and Cognitive Measures Serve as Preclinical Markers?
Objective: To examine whether individuals at increased risk of developing Parkinson’s disease (PD) show specific cognitive impairments suggestive of progression towards PD. Background: Olfactory deficits…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…
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