When and how to stop subthalamic deep brain stimulation in late-stage Parkinson’s disease
Objective: We sought to investigate the percentage of “poor stimulation responders” among late-stage Parkinson's disease (LSPD) patients for elaborating an algorithm to decide whether and…Correlation of Lead Location with Clinical Outcomes in a Double-Blinded Randomized Controlled Trial Evaluating Subthalamic Deep Brain Stimulation in Parkinson’s Disease (INTREPID)
Objective: To assess the relationship between lead location in the subthalamic nucleus (STN) and deep brain stimulation (DBS) outcomes as reported in the INTREPID clinical…Deep learning approach for Parkinson’s disease classification from facial expressions: A pilot feasibility study
Objective: To apply deep learning and traditional machine learning approaches to images of different facial expressions from patients and controls to aid in the prediction…Sustained Improvement in Freezing of Gait (FOG) and Treatment Satisfaction at 12 months After Initiation of Carbidopa/Levodopa Enteral Suspension (CLES) in Advanced Parkinson’s Disease (APD) Patients in USA: Interim Results from the PROviDE Study
Objective: To evaluate the long-term effectiveness of CLES on FOG and treatment satisfaction in APD patients. Background: FOG, prevalent in about 60% of APD patients,…High-frequency rTMS over the primary motor cortex relieves musculoskeletal pain in Parkinson’s disease: A randomized controlled trial
Objective: To study the effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) over primary motor cortex(M1) on musculoskeletal pain(MSP) in patients with Parkinson’s disease. Background:…Thiazolidinedione use is associated with reduced risk of Parkinson’s disease in patients with diabetes
Objective: This meta-analysis is aimed to explore the association between thiazolidinedione (TZD) use and Parkinson’s disease (PD) risk. Background: Recent epidemiological studies found protective effects of TZD class of drugs in…The genetic study of hereditary chorea in Kazakhstan
Objective: To analyze the genetic background of hereditary chorea in Kazakhstani population. Background: Hereditary chorea (HC) is a group of inherited movement disorders presenting with…Are New York City rail tracks harbingers for Parkinson’s disease?
Objective: To describe the clinical features of 7 New York City Metropolitan Transit Authority (NYC MTA) rail-track workers with Parkinson’s disease (PD) presenting to a…Can clinical outputs predict BDNF levels in people with Parkinson’s disease?
Objective: To modelling the relationship between Brain-Derived Neurotrophic Factor (BDNF) levels and clinical variables (stages of disease and cognition) in people with Parkinson's disease (PD).…Parkinson’s Disease Clinical Subtypes: Symptom Progression, Dementia, and Mortality
Objective: Identify Parkinson's disease (PD) clinical subtypes using multi-domain classification; determine subtype symptom progression; assess subtype clinical utility. Background: People with PD present with combinations…
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