The ROPAD (Rostock International Parkinson’s Disease Study) study: Towards defining the genetic epidemiology of the disease
Objective: ROPAD is an international, multicenter, epidemiological study that aims at a better understanding of the contribution of genetics to Parkinson’s disease (PD) based on…A novel peptide reduces α-synuclein levels and neurodegeneration in cell, invertebrate, and mammalian models of Parkinson’s disease
Objective: To identify and test the effectiveness of a novel peptide to reduce α-synuclein levels and neurodegeneration in cell and animal models of Parkinson’s disease…Inter-network connectivity dynamics underlie compensatory mechanisms in prodromal Parkinson’s disease
Objective: We aimed to investigate the dynamics of inter-network connectivity among non-manifesting GBA and LRRK2 mutation carriers. Background: The prodromal phase of Parkinson’s disease (PD)…Retinal thinning and disease worsening in Lewy body diseases
Objective: To assess longitudinal changes of retinal thickness measurements and their role as biomarkers of disease progression in patients with Lewy body diseases (LBDs). Background:…Brain cholinergic dysfunction in patients with isolated REM sleep behavior disorder: A clinical and 11C-Donepezil PET follow-up study
Objective: In this follow-up study, we aimed to explore the temporal changes in brain acetylcholinesterase activity and cognitive function of iRBD patients. Background: Isolated REM…Time Series Analysis Applied to EEG Shows Increased Global Connectivity During Motor Activation in PD Patients Compared to Controls
Objective: To apply time series analysis techniques to EEG studies to study connectivity changes during motor activation in a cohort of Parkinson´s disease subjects (PD)…Quantitative Autonomic Testing in Parkinson’s Disease
Objective: This study was done to find the clinical correlates with quantitative autonomic testing in Parkinson's disease. Background: Autonomic dysfunction is common and causes variety…Pet ownership associated with lower apathy and motor severity in female participants with PD
Objective: This study evaluated the impact of pet ownership on Parkinson’s disease (PD) severity and related symptoms. Background: PD is a common neurodegenerative disease characterized…Apomorphine improves pulmonary function in parkinsonian patients
Objective: Aim of the study; to investigate if apomorphine might facilitate weaning from mechanical ventilation in parkinsonian patients. Background: Apomorphine is an effective treatment for PD…The interaction of Parkin and TAF15 for the Drosophila in which neuronal defect was induced
Objective: Our study proposes a novel regulator for the protection of TAF15-induced proteinopathy and adds to our understanding of the exact pathogenic mechanism for TAF15-induced…
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