Are oromotor deficits a late stage signs in Parkinson’s disease?
Objective: To assess any preclinical signs of dysphagia in early PD. Background: Pre-clinical stages of Parkinson’s disease (PD) include the subtle signs of autonomic dysfunction,…Impact of Obstructive Sleep Apnea on Cognitive and Motor Functions in Parkinson’s Disease Patients
Objective: We conducted this systematic review and meta-analysis to assess the impact of OSA on cognitive and motor disorders in PD patients. Background: Parkinson’s disease…Clinical outcomes after DBS surgery in cognitively impaired patients with PD
Objective: To describe clinical outcomes after DBS in patients with PD and moderate cognitive impairment (CI). Background: DBS is generally contraindicated in PD patients with…The variants of autophagy genes of early-onset Parkinson’s disease
Objective: Early-onset Parkinson’s disease (EOPD) can be linked to different genetic backgrounds than non-EOPD. Therefore, we evaluated 52 patients with EOPD from 4 hospitals in…Association of Interleukin (IL)-2 and IL2RA gene polymorphisms with Parkinson’s disease in Taiwan
Objective: The purpose of this study is to investigate if interleukin 2 (IL-2) and interleukin 2 receptor alpha (IL2RA) genes are associated with Parkinson’s disease…LIPAD (LRRK2/Luebeck) International Parkinson’s Disease Study: Detecting genetic and environmental modifiers of penetrance and disease expression
Objective: The international multicenter LIPAD study is a deep-phenotyping, follow-up study to ROPAD (Rostock Parkinson’s Disease Study) with the aim to systematically characterize Parkinson's disease…Mass spectrometry-based proteomics brain analysis to distinguish between Parkinson syndromes
Objective: To address the gap existing during clinical diagnosis in differentiating among various forms of Parkinson syndrome (PS) by using mass spectrometry (MS)-based brain proteomics.…Exploring dopamine transporter single-photon emission computed tomography quantification as a measure of disease progression in idiopathic Parkinson’s disease
Objective: To evaluate the ability of DAT SPECT quantification to track disease progression in subjects with idiopathic Parkinson's disease (PD) by comparing baseline scans to…Frailty as clinical modulator of brain damage and progression in Parkinson’s disease
Objective: To evaluate the prevalence of frailty and correlation with motor and non-motor symptoms as well as MRI atrophy and white matter hyperintensities in Parkinson's…Utilization of a Visualization Software Tool for Deep Brain Stimulation Programming in a Subset of Subjects with Parkinson’s Disease Who Participated in the INTREPID Randomized Clinical Trial
Objective: This report will describe the utilization and parameters associated with the use of a new visualization tool for Deep Brain Stimulation (DBS) programming in…
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