Genomic variants associated with cognitive impairment in Parkinson’s disease: Ethnicity-specific GWAS
Objective: We aimed to identify the genomic variants that are associated with cognitive impairment in patients with Parkinson’s disease (PD). Background: Cognitive impairment is an…Long-Term Effects of LPS and Alcohol in Rats: A Model of Neuro-Degenerative Disease
Objective: We postulate alterations of the intestinal barrier (or leaky guts) enhances inflammation, as well as the production of alpga (α)-synuclein which has characteristic pathological…Swallowing assessment in Parkinson’s Disease using Dynamic Magnetic Resonance Imaging (dMRI)
Objective: To evaluate any dysphagia-signs in Parkinson’s disease (PD) with technique that is non-invasive, without-radiation-exposure and gives good soft-tissue contrast. Background: Swallowing, a basic oromotor…Metabolic syndrome and insulin resistance in Parkinson’s disease: could they affect motor or cognitive symptoms?
Objective: The objective of this work was to detect the markers of metabolic syndrome and insulin resistance in patients with PD and to study their…Non-motor symptoms and risk of functional dependency in early Parkinson’s disease
Objective: To determine whether non-motor symptoms predict the development of functional dependency in Parkinson’s disease (PD). Background: Non-motor symptoms are increasingly recognized as an integral…Cognitive dysfunction in patients with Parkinson’s disease and psychosis
Objective: The objective of this study was to explore the pattern of cognitive dysfunction in the patient's with Parkinson's disease and psychosis (PD-P) by comparing…Automated Metabolic Pattern Analysis in the Differential Diagnosis of Parkinsonism in a Swedish Cohort
Objective: To assess the accuracy of an automated, disease-specific, pattern model to distinguish among PD, MSA and PSP, in comparison with the final clinical diagnosis.…Investigating the cellular role of LRRK2 in the immune system
Objective: The objective of this project is to investigate the effect of Leucine Rich-Repeat Kinase 2 (LRRK2) dysfunction in the signalling mechanisms in macrophages and…The effect of baseline cognitive status of Parkinson’s disease on the outcome after deep brain stimulation surgery
Objective: To evaluate the effect of baseline cognitive status of Parkinson’s disease (PD) on the outcome after deep brain stimulation (DBS) surgery. Background: Advanced dementia…The contribution of cerebrovascular risk factors, metabolic and inflammatory changes to cognitive decline in Parkinson’s disease
Objective: To examine the contributions of systemic factors to clinically relevant cognitive decline in Parkinson’s disease (PD), we studied the impact of cardiometabolic and inflammatory…
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