Challenges in Parkinson’s Disease Diagnosis in a Patient with Ipsilateral Hemimelia
Objective: Our main objective is to demonstrate the challenges involved in the diagnosis of parkinsonism in a patient with transverse failure of formation of the…Stability and reliability of objective measures of speech in Parkinson’s Disease over 12 months
Objective: To describe the stability and reliability of acoustic measures of speech in Parkinson’s Disease (PD) at 3 and 12 months. Background: Speech biomarkers hold…Effects of Cognitively Challenging Agility Exercise Program on Clinical and Objective Measures in People with Parkinson’s Disease
Objective: To investigate the effects of a 6-week cognitively challenging exercise intervention in people with Parkinson’s disease (PD). Background: Gait and balance impairments have been…Formulations and evaluations of Intranasal Nose to Brain Delivery of Curcumin with resveratrol Nanoparticle for treatment of Parkisonism
Objective: Parkinson’s disease (PD) is a common neurodegenerative disease characterized by motor symptoms of tremor, rigidity, bradykinesia, and postural instability. Growing evidence indicates that resveratrol…A pilot study of the feasibility and effects of table tennis training in Parkinson’s Disease
Objective: To investigate the feasibility and effects of table tennis training on balance control and physical function in individuals with Parkinson’s disease (PD). Background: Postural…Exploring anti-hypertensives as possible disease modifying agents in Parkinson’s disease using artificial intelligence and epidemiology
Objective: To apply machine learning and epidemiology to identify existing drugs that may have a disease modifying effect in Parkinson’s disease (PD). Background: Drug repurposing…Psychosis in Prodromal Parkinson’s disease
Objective: To investigate a possible association between psychosis and prodromal Parkinson’s disease (PD) in a population-based cohort, the Hellenic Longitudinal Investigation of Aging and Diet…Parkinsonism and other motor features in familial frontotemporal dementia with mutations in the MAPT, GRN, or C9orf72 gene (LEFFTDS cohort)
Objective: We compared motor features in patients with familial frontotemporal dementia (f-FTD) and MAPT, GRN or C9orf72 gene mutations. Special emphasis was placed on the evaluation…The role of X-chromosome inactivation in the penetrance of X-linked dystonia-parkinsonism in women
Objective: To investigate whether the combination of the X-linked dystonia-parkinsonism (XDP) haplotype and skewed X-chromosome inactivation (XCI) underlies the penetrance of XDP in women. Background:…Digenic inheritance of WARS2 and CHRNA6 mutations in infantile parkinsonism
Objective: To provide evidence of digenic inheritance in infantile parkinsonism. Background: Oligogenic inheritance has been demonstrated in PD[1],where patients with a primary genetic cause can…
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