Sleep Abnormalities in patients with Parkinson’s disease having REM sleep behaviour disorder with and without Psychosis
Objective: To study the polysomnographic changes in patients of Parkinson’s disease with or without psychosis and evaluate any microarchitecture and microarchitecture changes. Background: Parkinson’s disease…Objective monitoring of drug response in early PD patients using remote, at-home typing data through machine learning analysis
Objective: We designed an algorithm to detect response to medication in an early PD population using at-home, unsupervised, unobtrusive typing data. Background: Advances in technology…Re-emergent Tremor in Parkinson’s Disease
Objective: The aim of the study was to evaluate the occurrence and the clinical characteristics of re-emergent tremor in a population of patients with PD.…Characteristics in relation to demographic, disease related and clinical variables of a cohort of Parkinson’s disease patients from Northern Sri Lanka
Objective: To evaluate motor and non-motor domains, as well as for demographic and disease related characteristics of patients with Parkinson’s disease and the relations with…Evaluation of the relationship between Leucine-rich repeat kinase 2 (LRRK2) S1647T variants and smoking with risk of Parkinson’s Disease in the Singapore population
Objective: To investigate whether cigarette smoking influences the relationship between S1647T variants and risk of PD in the Singapore population. Background: Case-control studies in southern…A review of modifiers of Parkinsonism in the Leucine-rich repeat kinase 2 (LRRK2) population
Objective: To review and examine the most current identified modifiers of Parkinsonism in the LRRK2 population. Background: LRRK2 is a protein with multiple domains and…Loss of VPS29 disrupts retromer function and synaptic transmission, leading to neurodegeneration in Drosophila
Objective: To understand the role of the retromer complex in the central nervous system(CNS), and its link to Parkinson's disease (PD) susceptibility. Background: Mutations in…Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…Abnormal Functional Connectivity in Cerebellar Locomotor Region is associated with the severity of freezing of gait in patients with Parkinson’s disease
Objective: We aim to analyze cerebellar functional connectivity (FC) in PD patients with FOG (PD-FOG). Background: Freezing of gait (FOG) is a disabling disorder frequently…Semi-automated segmentation and quantification of the substantia nigra depigmentation in Parkinson’s disease – a multicentre case control MRI study in 284 participants
Objective: To provide a semi-automated segmentation and quantification method of the changes in the substantia nigra (SN) in Parkinson’s disease (PD) using neuromelanin (NM)-sensitive MRI…
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