Alpha-synuclein oligomer and rotenone treatments injury the dopaminergic neuron via inhibiting the expression of gene SEMA6D
Objective: To investigate the expression of Semaphorin6D (SEMA6D) and its interaction with Plexin-A1 in cellular Parkinson's disease(PD) models induced by α-synuclein and rotenone. Background: In…Functional Balance and Neuromuscular Strength Difficulties Like Fracture Predictors in a Parkinsonian Population
Objective: To evaluate the strength and function of the hip flexor muscles and knee extensors of elderly patients with Parkinson's disease (PD) to know possible…Clinical study on the correlation between Parkinson’s somatosensory evoked potentials and STN-DBS parameters
Objective: Indications for STN-DBS are assessed based on the clinical symptoms. Our test was a clinical study on the correlation between amplitude and latency of…Effects of PGE inhibition on Striatal Neuroinflammation in 6-OHDA lesion
Objective: In this study, we investigated the role of prostaglandin E2 inhibition, pro-inflammatory cytokine concentration and microglial activation in a Parkinsonian rat Background: Neuro-inflammation plays…Carbon Monoxide Poisoning-Induced Parkinsonism: A Prospective Study of Clinical and Neuroimage Correlation
Objective: To investigate prospectively the nigrostriatal system in patients with delayed post-anoxic Parkinsonism by TRODAT-1 brain SPECT serially and to correlate the neuropsychiatric performance and…SYN120 (a Dual 5-HT6/5-HT2A Antagonist) Study to Evaluate Safety, Tolerability and Efficacy in Parkinson’s Disease Dementia (SYNAPSE): Phase 2a Study Results
Objective: To evaluate the safety and preliminary efficacy of SYN120 in patients with Parkinson's disease dementia (PDD). Background: SYN120 is an antagonist of serotonin receptors…Outcomes of a Prospective, Multi-center International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: The objective this report is to describe collected outcomes from a large scale registry of a Deep Brain Stimulation (DBS) system capable of Multiple…Update on The Personalized Parkinson Project: Partnering with Patients to Understand Disease Progression Through a Multi-Dimensional Approach
Objective: Enrollment for The Personalized Parkinson Project (PPP) is underway. Co-design and mutual partnership between patients and researchers is a key characteristic of the project…Contribution of ATP-sensitive potassium channels in the subthalamic nucleus neurons towards Parkinson’s disease
Objective: This study describe a quantitative investigation to explore the modulating effects of the ATP-dependent Potassium channel (KATP) ion channel conductance on spike patterns in…Remotely supervised home-based aerobic exercise for Parkinson patients
Objective: To evaluate: (1) the adherence to long-term home-based aerobic exercise (AE) in patients with Parkinson’s disease (PD); and (2) whether AE affords clinically relevant…
- « Previous Page
- 1
- …
- 250
- 251
- 252
- 253
- 254
- …
- 405
- Next Page »