Daughter’s ataxia reveals father’s genetic Parkinsonism. The first reported case of Spinocerebellar ataxia -15 presenting with levodopa responsive hemi Parkinsonism
Objective: A 38 year old Australian florist of Anglo-Celtic origin described two years of difficulty using his right hand with associated sensory disturbance attributed initially…Non-invasive, automated corneal nerve quantification reveals neurodegeneration in Parkinson’s disease: A potential novel imaging biomarker
Objective: The aim of the study is to use automated analysis of corneal confocal microscopy (CCM) images to allow rapid and reliable quantification of corneal…Three Tesla susceptibility-weighted MR imaging of parkinsonism and idiopathic REM sleep behavior disorder: Comparison with 123I-FP-CIT SPECT
Objective: The aim of this study was to assess the diagnostic performance of 3 Tesla susceptibility-weighted MRI (3T-SWI) and the concordance between the loss of…Unilateral abnormal dopamine transporter (DaT) scans: Early indicator of Parkinson’s disease and degenerative Parkinsonism
Objective: In this study, we aimed to determine the relevance of unilateral abnormal dopamine transporter (DaT) scans in patients presenting with clinically uncertain Parkinsonian syndromes…Efficacy of incobotulinumtoxinA in patients with sialorrhea, as assessed using the modified Radboud Oral Motor Inventory for Parkinson’s disease (mROMP): Results of the SIAXI study
Objective: The pivotal double-blind, randomised Phase III SIAXI study (NCT02091739), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U for sialorrhea. Co-primary endpoints…Early stage Parkinson’s disease phenotypes
Objective: Identify Parkinson’s disease (PD) subpopulation clusters present at disease onset using a number of motor and non-motor phenotypes. Background: PD is considered a syndrome,…Is Heart Rate variability a differential biomarker in REM sleep behavior disorder, Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy?
Objective: Heart rate deceleration capacity (DC) and heart rate variability index (HRVI) as potential biomarkers for autonomic dysregulation were studied in subjects (each group N=10)…Dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder
Objective: This study is to investigate the correlations between the abnormalities in the distribution of striatal dopamine transporter (DAT) and the expression of Parkinson's disease…Unveiling the function of altered gut microbiota composition in Parkinson’s disease
Objective: To investigate the gut microbiome and metabolome in Parkinson’s disease (PD). Background: Recent evidence revealed that gut microbes promote alpha-synuclein pathology and motor deficits…Bone health and laboratorial correlations of Vitamin D in Parkinson’s disease
Objective: To evaluate the correlation between levels of 25 (OH)D (Vitamin D) and Bone Mineral Density (BMD) in a parkinsonian population. Background: Considering a limiting…
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