Cell and animal models lacking RAB39B show biochemical and behavioural phenotypes that model aspects of Parkinson’s disease
Objective: To determine the pathogenic mechanisms underlying RAB39B-mediated Parkinson’s disease (PD). Background: PD is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the…Microbiota DNA in the blood of patients with Parkinson’s disease
Objective: The aim of this study was to explore the blood microbiota compositions in Chinese patients with Parkinson’s disease (PD). Background: Emerging evidences suggest that…α-synuclein antibody 5G4 identifies manifest and prodromal Parkinson’s disease in colonic mucosa
Objective: The aim of this study was to evaluate colonic mucosa staining using the 5G4 antibody, specific only for the disease-associated form of α-synuclein, in…Naturalistic-based UPDRS-III Minimal Clinically Important Difference (MCID) in early PD
Objective: To find the MCID of the UPDRS-III subscale in early PD subjects, when started on a new dopaminergic drug. Background: The concept of Minimally…Effect of PD medication on disease progression as measured by rate of change in MDS_UPDRS and DaT SBR in PPMI study
Objective: In clinical trials for new PD therapies, it is common for patients to start to take approved symptomatic PD medications during the study. The…Brief Cognitive Screening for Parkinson’s disease by the Korean Version of the Montreal Cognitive Assessment
Objective: We evaluated the screening ability of the Korean version of the Montreal Cognitive Assessment (K-MoCA) in the patients with Parkinson's disease. Background: The Montreal…Perry syndrome: Proposal of international diagnostic criteria and a new disease concept
Objective: To propose international diagnostic criteria for Perry syndrome and a new disease concept. Background: Perry syndrome is a rare autosomal dominant neurodegenerative disease characterised…The effects of STN-DBS on the Parkinson’s disease patients with different progressive rates
Objective: The aim of this study is to explore the effects of STN-DBS on the Parkinson's disease patients with different progressive rates Background: Studies indicate…Clinical effectiveness of a highly challenging balance training (HiBalance program) for Parkinson’s disease: A multi-center clinical effectiveness trial
Objective: To determine the effectiveness of the adapted HiBalance program on balance control and gait among people with mild-moderate PD when performed in multiple clinical…Peripheral nerve grafts implanted into the substantia nigra in patients with Parkinson’s disease during deep brain stimulation surgery: 2-year follow-up study of gait parameters
Objective: Measuring gait parameters in patients with Parkinson's disease (PD) who underwent autologous peripheral nerve grafts implantation (surgical deployment of the Schwann cells obtained from…
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