Rolipram, a PDE-IV inhibitor protects against experimental Parkinsonism in mice
Objective: Rolipram, a specific inhibitor of the phosphodiesterase IV (PDE IV), has recently been shown to exert neuroprotective effects in an Alzheimer transgenic mouse model…Parkinsonism Revealing Cerebral Hematoma with Moya Moya Disease
Objective: The aim of this study is to describe a rare cause of parkinsonism. Background: Moyamoya disease (MMD), a rare chronic, progressive cerebrovascular disease leads…Mindfulness for People with Parkinson’s: Emotional Well Being, Social Support and Group Effect
Objective: ObjectiveTo investigate the effects of a 8-week MBSR group training on the quality of life of People with Parkinson's (PwP). Background: Little is known…Deep Brain Stimulation for Parkinson’s disease: Short-term outcomes, referral patterns and health disparities.
Objective: To describe the practice patterns at University of Miami (UM), short term outcomes and health disparities among ethnic groups. Background: Deep brain stimulation (DBS)…Factors determining the motor outcome of STN DBS in PD patients: Evidence for Dual Actions
Objective: We investigated factors determining the motor outcome of STN DBS in patients with Parkinson disease (PD). Background: The STN DBS has revolutionized the management…Risk of Parkinson’s disease in zolpidem user: A systematic review and meta-analysis
Objective: To explore the association between zolpidem use and risk of Parkinson's disorder. Background: Zolpidem is commonly prescribed for the treatment of sleep disorder. Epidemiological…Impaired stress-induced mitophagy in parkinsonian LRRK2(R1441G) knockin mutant mice
Objective: 1. Morphological changes and accumulation of ubiquitinated mitochondria in the striatum of aged leucine-rich-repeat kinase 2 (LRRK2)R1441G knockin mutant mice (Liu et al., 2014,…Prognostic relevance and predictive ability of data-driven PD subtypes in the Longitudinal and Biomarker Studies in Parkinson’s disease (LABS-PD)
Objective: To assess the prognostic relevance and predictive ability of a PD subtype classification system generated in LABS-PD cohort. Background: PD subtype classification systems have…Plasma Biomarkers in Idiopathic Normal Pressure Hydrocephalus
Objective: (1) To investigate the role of plasma biomarkers that is known to related to Alzheimer’s disease in INPH(2) To assess the diagnostic and prognostic…Does Parkinsons KinetiGraph (PKG) recording help in clinical decision making? A local experience
Objective: To evaluate the use of the PKG to aid clinical management decisions in a district general hospital. Background: Clinicians treating Parkinson's disease (PD) must…
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