Feasibility of using a smartphone application for the objective evaluation of Parkinson disease
Objective: To determine the feasibility, reliability, and value of using a smartphone application to longitudinally track motor and non-motor features of Parkinson disease (PD). Further,…Does smoking impact dopamine neuronal loss in de novo Parkinson’s disease?
Objective: To investigate whether smoking impacts striatal dopamine neuronal degeneration in Parkinson’s disease (PD), we compared striatal subregional dopamine transporter (DAT) binding between current-smokers and…Marked occipital hypometabolism on FDG-PET in patients with idiopathic RBD may predict Parkinson’s disease
Objective: In the present study, we tried to elucidate if the occipital hypometabolism detected by [(18) F]-fluoro-d-glucose (FDG) positron emission tomography (PET) scan in patients with idiopathic…Altered PDE10A Expression Detectable Early in Untreated Parkinson’s Disease Patients
Objective: To investigate in vivo whether loss of PDE10A expression in Parkinson’s disease (PD) is an early phenomenon in early untreated PD patients using positron…APOE4+ status increases rate of longitudinal cognitive decline in Parkinson Disease patients with low CSF Aβ42
Objective: To determine if the presence of APOEɛ4 allele (APOE4+) predicts longitudinal cognitive decline in Parkinson’s disease (PD) patients with low CSFAβ42 Background: Cognitive impairment…Increased BMI May Protect Against Parkinson’s Disease: Evidence From A Mendelian Randomisation Study
Objective: To use two-sample Mendelian randomisation (MR) to study the causal effect of body mass index (BMI) on Parkinson's disease (PD). Background: Both positive and…Extreme Premature Ejaculation in Parkinson’s disease
Objective: To describe the nature of premature ejaculation (PE) in a series of male patients with Parkinson's disease (PD), with recent complaints of PE that began…Central Aortic Pressure in Parkinson’s Disease and Levodopa Effect
Objective: Central aortic pressure (CAP) is the systolic blood pressure at the root of the aorta. In young people CAP is lower than the peripheral…Self-rated burden grading of nonmotor symptoms identifies landmarks and subtypes of Parkinson’s disease: first report from a Moscow-Madrid-London collaboration
Objective: To describe clinical and imaging biomarkers of nonmotor symptoms burden (NMSB) as defined by NMS questionnaire (NMSQ) scores in a prospective international cohort study…Do median-nerve evoked blink reflexes allow early differentiation between PD and PSP in patients with debuting parkinsonism?
Objective: Do median-nerve elicited blink reflex responses enable early differentiation between PD and PSP in patients with idiopathic parkinsonism? Background: Differentiation between PD and PSP in…
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