Genetic outcomes of South Asian Parkinsonism cohort: from a tertiary care hospital
Objective: To identify the genetic heterogeneity in 16 south Asian patient with Parkinson’s disease. Background: Parkinson’s disease(PD) is the second most progressive neurodegenerative disorder with…Effect of the 5-HT2A/2C inverse agonist nelotanserin on dyskinesia in the MPTP-lesioned marmoset
Objective: To determine the effect of the serotonin 2A/2C (5-HT2A/2C) receptor inverse agonist nelotanserin on dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset. Background: Nelotanserin is a…Reaching the hard-to-reach: the representativeness of patients with parkinsonism recruited to the PRIME-UK cross-sectional study
Objective: To recruit a more representative population of patients with parkinsonism (PwP) focusing on those often excluded from research. Background: PwP who are older, living…An Interesting Case of COVID-19 related Parkinsonism
Objective: Virus related Parkinsonism causing encephalitis lethargica has been documented in the literature. The novel Coronavirus (COVID-19) has been linked to a small number of…A comparative analysis of vegetative disorders in Parkinson`s disease and vascular parkinsonism.
Objective: Comparative analysis of vegetative disorders (VD) in Parkinson's disease and vascular parkinsonism. Background: Vegetative disorders (VD) are one of the most common nonmotor disorders…Effect of Best Practice Advisory on the administration of contraindicated medications to hospitalized patients with Parkinson’s disease and related disorders
Objective: To determine if a best practice advisory (BPA) reduced the orders and administration of contraindicated dopamine blocking agents (DBA) to hospitalized patients with Parkinson’s…Narrative review of the efficacy of the efficacy of transcranial magnetic stimulation with patients with Parkinson disease.
Objective: To evaluate the efficacy of transcranial magnetic stimulation with patients with Parkinson diseases. Background: Parkinson's disease is one of the most common causes of…Asymmetric and profound nigrostriatal dopaminergic dysfunction in Parkinson’s disease with preceding REM sleep behavior disorders
Objective: To investigate the differences in the pattern of nigrostriatal and pontine monoaminergic degeneration patients with de novo Parkinson's disease (PD), stratified by the presence…Classification and genotype-phenotype relationships of GBA1 variants and Parkinson’s disease: MDSGene Systematic Review
Objective: To provide a comprehensive and systematic literature review of variants in the glucocerebrosidase 1 gene (GBA1) linked to Parkinson’s disease (PD). Background: Approximately 10% of patients with PD…Bowel symptoms and management practices in Parkinson’s disease and related conditions: results from the PRIME-UK study.
Objective: To describe bowel symptoms and constipation management practices in a large, representative cross-sectional study of Parkinson’s and related disorders. Background: Bowel symptoms, particularly constipation,…
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