Impact on Dyskinesia in Advanced Parkinson’s Disease Patients Treated with LCIG: Analysis from the COSMOS Study
Objective: Analyze the impact of levodopa-carbidopa intestinal gel (LCIG) treatment on dyskinesia duration and severity in advanced Parkinson’s disease (APD) patients participating in the COSMOS…Quantitative susceptibility mapping and blood neurofilament light chain differentiate between parkinsonian disorders
Objective: We employed Quantitative susceptibility mapping (QSM) to assess iron deposition in a larger sample size and explore whether combining QSM and NfL can improve…A case of dystonia-parkinsonism associated with a heterozygous PRKRA (DYT16) gene mutation
Objective: We describe the clinical presentation, diagnosis, and treatment of a case of dystonia-parkinsonism associated with a heterozygous mutation in the initiator methionine of the…Perivascular spaces in the basal ganglia and long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between enlarged perivascular spaces (PVSs) in the basal ganglia (BG-PVSs) and long-term motor outcomes in Parkinson’s disease (PD). Background: PVSs…Mood is a Key Factor in Progression of Non-Motor Symptoms Burden in Parkinson´s disease.
Objective: The aim of the present study was to identify predictors of non-motor symptoms burden non-progression (NMSB-NP) in PD patients from a Spanish cohort [1,2].…Maximising UPDRS information while minimising assessment time
Objective: The gold standard for measuring disease severity in PD (Parkinson’s Disease) is the MDS-UPDRS (Movement Disorder Society - Unified PD Rating Scale) [1]. However,…Clinical variants of PSP: phenotypical convergence and its relationship with the brain glucose metabolism
Objective: To evaluate the phenotypical convergence phenomena among a cohort of different PSP variants. We also aimed to evaluate the possible correlations of the regional…Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Impact of Concomitant Antiemetics on Nausea and Vomiting
Objective: Analyze the effect of concomitant trimethobenzamide (TMB) on nausea and vomiting rates in patients with Parkinson’s disease (PD) receiving apomorphine sublingual film (APL) for…LY-487,379 alleviates parkinsonism when administered as monotherapy in the MPTP-lesioned marmoset
Objective: To determine the effect of selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulation as monotherapy on parkinsonism, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset. Background: We…Mild parkinsonian signs in older adults correlate with an impaired functional level – a cross-sectional general population study from the “Good Aging in Skåne” cohort
Objective: We aimed to investigate the prevalence of MPS and the association with Activities of Daily Living (ADL), cognitive, physical, and autonomic function in adults…
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