Prevalence of GBA parkinsonism in Slovak Parkinson’s disease population
Objective: Our study aimed to determine the prevalence of GBA parkinsonism in the Slovak population with Parkinson's disease (PD). Background: In recent years, there has…Effects of gait symmetry manipulation on cortico-subthalamic interhemispheric coupling in parkinsonian patients by use of virtual reality
Objective: The aim of this study is 1) to characterize gait-related neuronal oscillations and functional connectivity changes between cortico-subthalamic network nodes in Parkinson´s disease (PD)…NPC1 is not a PD risk factor gene
Objective: To test the hypothesis of NPC1 to be a PD risk factor gene. Background: The many etiologies of PD include genetic risk factors. The…CCDC88C p.R464H likely cause a novel late-onset parkinsonism phenotype
Objective: We describe two sisters with late-onset parkinsonism associated with a CCDC88C variant (p.R464H). Background: Tsoi et al. (2014) identified a heterozygous missense mutation in the CCDC88C gene (R464H), by…COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…Contribution of external globus pallidus to motor deficits of Parkinson’s disease: optogenetic studies in murine model
Objective: The present study explored whether altered activity of external globus pallidus (GPe) neurons contributes to the development of motor deficits of Parkinson’s disease (PD).…Intensive Multimodal Rehabilitation Intervention for Moderately Advanced Parkinson’s Disease
Objective: To measure the impact of intensive multimodal neurorehabilitation in patients with moderately advanced with Parkinson’s disease (PD) Background: Dedicated neurorehabilitation is an essential part…Delayed post-stroke parkinsonism: description of two cases and possible mechanism
Objective: To present two patients who developed delayed parkinsonism years after experiencing midbrain strokes and to suggest a possible mechanism for this delayed phenomenon. Background:…Diagnostic Utility of I123-FP-CIT Single Photon Emission Computed Tomography for Patients with Clinically Uncertain Parkinsonian Syndrome
Objective: This study investigated the impact of I123-FP-CIT single photon emission computed tomography (SPECT) for the diagnosis of patients with clinically uncertain parkinsonian syndrome (CUPS)…Serum Metabolomic Characterization of PLA2G6-associated Dystonia-Parkinsonism: a case-control biomarker study
Objective: PLA2G6 is the causative gene for autosomal recessive Dystonia-Parkinsonism (PARK14). This case-control biomarker study aimed to test serum metabolomics of patients diagnosed as PARK14.…
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