Amelioration of Levodopa-induced Dyskinesias using Genetic Silencing of Striatal CaV1.3 in Parkinsonian Rats: Impact of Sex and Advancing Age
Objective: To advance understanding of striatal CaV1.3 (cacna1d) channel silencing as a therapeutic approach to reduce levodopa-induced dyskinesias (LID), a side effect of long-term escalating…Activity and sleep associated with changes in glymphatic imaging-markers in Parkinson Disease patients enrolled in 3-month exercise program
Objective: To investigate whether intensity of activity and quality of sleep during a 3-month exercise program for patients with Parkinson Disease (PD) are associated with…The role of Parkinson Nurses for personalizing care in Parkinson’s Disease: a systematic review and meta-analysis
Objective: To identify the various roles and functions that Parkinson Nurses (PNs) may hold for personalized care of Patients with Parkinson’s (PwPs). Providing a systematic…Sleep Disorders in Normotensive Hydrocephalus
Objective: Objective of the work was to study the prevalence of sleep disorders, Rem Sleep Behaviour Disorder (RBD) and obstructive sleep apnea (OSA) in patients with NPH.…The correlation between genetic factors and freezing of gait in patients with Parkinson’s disease
Objective: We aimed to evaluate the association of six selected polymorphism of DRD2, ANKK1, and COMT genes with the occurrence of freeying of gate (FOG),…In vivo synaptic density in parkinsonism
Objective: To provide first evidence of in vivo binding properties of the [18F]SynVesT-1 tracer (aka [18F]-SDM-8) for the quantification of synaptic density loss in a…Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Advance Care Planning and Parkinson’s disease: patient knowledge assessment
Objective: Evaluate disease knowledge in patients with Parkinson’s disease in an Advance Care Planning (ACP) clinic. Background: Poor disease knowledge has been associated with misconceptions…Adults with slowly progressive dystonia-parkinsonism secondary to manganese accumulation
Objective: To expand the clinical spectrum of manganese-induced neurodegeneration. Background: Neurodegeneration induced by manganese accumulation is a potentially treatable condition and therefore should not be…Association of type 2 diabetes and dementia in elderly patients with Parkinson’s disease: a population-based study in Korea
Objective: This study aimed to investigate the impact of type 2 diabetes (T2DM) on the development of dementia in patients with Parkinson’s disease (PD). Background:…
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