Plasma Exosomal Cytokines as Longitudinal Biomarkers and Predictors of Parkinson’s Disease Progression
Objective: To determine whether plasma exosomal cytokines can serve as stable biomarkers of disease progression in Parkinson’s disease (PD) and to evaluate their utility in…Relationships of serum & CSF Transcobalamin Receptor Antibodies to CSF vitamin B12, holotranscobalamin and clinical progression in Parkinson’s disease
Objective: To measure serum & CSF transcobalamin receptor antibodies (CD320ab) in patients with early Parkinson’s disease (PD) and to assess their relationships to CSF vitamin…Switching to IPX203 Significantly Increases the Duration of “Good On” Intervals: Interim Real-World Results from the First 111 Patients in ELEVATE-PD
Objective: Evaluate the impact of IPX203 on the duration of “Good On” intervals and daily motor fluctuations in patients with PD after switching from other…Cross-Family Analysis of Rare Deleterious Variants Segregating in Families with Parkinson’s Disease
Objective: To identify potential novel variants and genes associated with Parkinson’s disease (PD) in multiplex families. Background: Identifying novel genes associated with PD is critical…Categorization and Characterization of Cognitive Phenotypes in Parkinson’s Disease Using Machine Learning.
Objective: To categorize cognitive phenotypes in patients with Parkinson's Disease (PD) using an unsupervised algorithm and validate their clinical, psychiatric, and motor differences. Background: Four…Association between probable RBD and reduced CSF 5-hydroxyindoleacetic acid levels in Parkinson’s disease
Objective: To investigate the association between probable RBD (pRBD) and cerebrospinal fluid (CSF) levels of 5-hydroxyindoleacetic acid (5-HIAA), a serotonin metabolite, in patients with Parkinson’s…Automated Identification of Freezing of Gait in Parkinson’s Disease Using Q-Learning Analysis during Virtual Reality–Based Gait Task
Objective: To investigate whether a virtual reality (VR)-based gait task can induce freezing of gait (FOG) in Parkinson’s disease (PD) and whether gait trajectory data…Tremorography as an objective marker of the response after MRgFUS VIM in essential tremor and Parkinson’s disease
Objective: To assess tremorography as an objective tool for evaluating response to MR-guided focused ultrasound (MRgFUS) ventral intermediate nucleus (VIM) thalamotomy in essential tremor (ET) and Parkinson’s…Cognitive Impairment and Neuropsychiatric Manifestations in Parkinson’s disease in Africa: A Systematic Review of Evidence
Objective: To critically appraise and synthesize evidence on the prevalence and clinical correlates of cognitive impairment and neuropsychiatric manifestations among patients with Parkinson’s disease in…Multi-Sequence MRI-Based Machine Learning Model for Differentiating Parkinson Disease (PD) from Multiple System Atrophy (MSA)
Objective: To develop a multi-sequence MRI-based machine learning model differentiating PD from MSA. Background: MRI protocols capable of distinguishing PD from MSA are greatly needed.…
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