Combined effect of polygenic background and GBA Pathogenic variants in Parkinson’s disease risk
Objective: We aimed to investigate whether polygenic background affects the penetrance of Parkinson’s disease (PD) among carriers of heterozygous pathogenic variants (PV) in GBA. Background: Several rare homozygous mutations within…Potential role of Alpha-synuclein levels in Platelets in GBA-related PD
Objective: Identification of a blood biomarker to predict PD diagnosis or to monitor the disease progression. Background: Previous evidence suggests differences in systemic alpha-synuclein levels…Neuropsychological and quality of life outcome comparison after awake and asleep pallidal deep brain stimulation (DBS) surgery for Parkinson’s disease
Objective: To compare cognitive, psychiatric and quality of life (QoL) outcomes after awake and asleep bilateral pallidal (GPi) deep brain stimulation (DBS). Background: Prior studies…Dopamine depletion of striatal subregions and motor dysfunction in prodromal and clinical Parkinson’s disease
Objective: This aim of this study was to investigate how dopamine depletion of different striatal subregions contributes to motor symptoms in patients with prodromal and…REM sleep behaviour disorder in Parkinson’s disease: prevalence and correlation with other sleep parameters
Objective: to assess the prevalence of probable rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD) patients and its correlation with other…Vagus nerve degeneration in Parkinson’s disease: correlation with autonomic symptoms and pupillography
Objective: To test the hypothesis that vagus nerve (VN) atrophy is pronounced in the body-first subtype of Parkinson’s disease (PD) and coincides with pupillary dysfunction.…Filipino’s and Parkinson’s Disease: A Scoping Review of the Literature
Objective: To review the literature on Parkinson’s disease (PD) in Filipino’s and identify specific studies focusing on Filipino-Americans and Parkinson’s disease. Background: Filipino’s are the…Online recruitment and retention in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: To describe participants and retention in the longitudinal PPMI Online cohort Background: The overall PPMI aim of biomarker identification to enable therapeutic development is…MR-guided focused ultrasound pallidothalamic tractotomy in non-tremor dominant (akinetic-rigid) Parkinson’s disease treatment
Objective: The study aims to show that unilateral MR-guided focused ultrasound (MRgFUS) treatment akinetic-rigid Parkinson's disease (PD) can be safe and effective. Background: Parkinson's disease…From the Healthy Brain Ageing (HeBA) Cohort: Frequency of key risk factors for Parkinson in a European Cohort
Objective: To present the baseline data on common risk factors for Parkinson’s disease (PD) in the population-based cohort of the HeBA study (Ref Poster 1)…
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