Effects of NE3107 anti-inflammatory treatment on motor activity and neurodegenerative features of Parkinson’s disease in a marmoset monkey model
Objective: To demonstrate the effects of an oral, anti-inflammatory agent, NE3107, on motor activity, levodopa-induced dyskinesia (LID) induction, and neuron survival in a marmoset model…Clinical progression in males and females with early treatment-naive Parkinson’s disease
Objective: To investigate differences in the progression of motor and non-motor symptoms and striatal degeneration between males and females with Parkinson’s disease (PD). Background: Biological…STRAT-PARK: a biomarker and stratification initiative for Parkinson’s disease
Objective: The STRAT-PARK initiative aims to stratify Parkinson’s disease (PD) according to underlying molecular mechanisms, and to develop clinically applicable biomarkers for patient stratification. Background:…Navigating Open Science in Canada with the Canadian Open Parkinson Network
Objective: The Canadian Open Parkinson Network (C-OPN) is a pan-Canadian initiative that bridges people, data and resources to accelerate new discoveries in the field of…Comparison of original and revised versions of the University of Pennsylvania Smell Identification Test
Objective: To assess agreement between the original and revised versions of the University of Pennsylvania Smell Identification Test (UPSIT). Background: Recently published age/sex-specific UPSIT percentiles,…Modeling Parkinson’s disease progression accounting for the effect of symptomatic treatments in the Parkinson’s Progression Markers Initiative study
Objective: To explore the natural history of Parkinson’s disease (PD) accounting for the effect of symptomatic treatments on progression by modeling the time course of…Preliminary results of the validation study of the Shame in Parkinson’s disease (SPARK) Scale
Objective: The goal of this study is to validate the Shame in PARKinson’s disease (SPARK) Scale [1] which identifies the presence, the extent and some…Artificial intelligence for the improvement of imaging biomarkers in Parkinson’s disease
Objective: To systematically review the current literature on the application of artificial intelligence (AI) for imaging biomarkers in Parkinson's disease (PD) and to identify translational…Estimating the Incidence of Parkinson’s Disease in Patients with Epilepsy: A Nationwide Cohort Study in South Korea
Objective: We aimed to estimate the incidence of PD in patients with epilepsy and explore the association between epilepsy and PD. Background: Although epilepsy is…Effect of Sex on the association between GBA mutations and Cognitive Decline in Parkinson’s Disease
Objective: To assess the impact of sex and glucocerebrosidase (GBA) mutations on cognitive trajectories in a sample of Parkinson's disease (PD) patients. Background: Accumulating evidence…
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